KEGG   ENZYME: 4.2.3.144Help
Entry
EC 4.2.3.144                Enzyme                                 

Name
geranyllinalool synthase;
TPS04/GES;
GES
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranylgeranyl diphosphate diphosphate-lyase ((E,E)-geranyllinalool-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate [RN:R10533]
Reaction(KEGG)
Substrate
geranylgeranyl diphosphate [CPD:C00353];
H2O [CPD:C00001]
Product
(E,E)-geranyllinalool [CPD:C20681];
diphosphate [CPD:C00013]
Comment
The enzyme is a component of the herbivore-induced indirect defense system. The product, (E,E)-geranyllinalool, is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT), which is released by many plants in response to damage.
History
EC 4.2.3.144 created 2013
Pathway
Diterpenoid biosynthesis
Orthology
K17982  
geranyllinalool synthase
Genes
ATH: 
AT1G61120(TPS04)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
VRA: 
MTR: 
PPER: 
PMUM: 
MDM: 
PXB: 
RCU: 
JCU: 
POP: 
POPTR_0004s03810g(POPTRDRAFT_857018) POPTR_0004s04090g(POPTRDRAFT_758919)
VVI: 
SLY: 
SPEN: 
SOT: 
BVG: 
NNU: 
PDA: 
EGU: 
MUS: 
ATR: 
 » show all
Taxonomy
Reference
1  [PMID:18398052]
  Authors
Herde M, Gartner K, Kollner TG, Fode B, Boland W, Gershenzon J, Gatz C, Tholl D
  Title
Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT.
  Journal
Plant. Cell. 20 (2008) 1152-68.
  Sequence
[ath:AT1G61120]
Reference
2  [PMID:18842097]
  Authors
Attaran E, Rostas M, Zeier J
  Title
Pseudomonas syringae elicits emission of the terpenoid (E,E)-4,8,12-trimethyl-1,3,7,11-tridecatetraene in Arabidopsis leaves via jasmonate signaling and expression of the terpene synthase TPS4.
  Journal
Mol. Plant. Microbe. Interact. 21 (2008) 1482-97.
  Sequence
[ath:AT1G61120]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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