KEGG   ENZYME: 4.2.3.33Help
Entry
EC 4.2.3.33                 Enzyme                                 

Name
stemar-13-ene synthase;
OsDTC2;
OsK8;
OsKL8;
OsKS8;
stemarene synthase;
syn-stemar-13-ene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming)
Reaction(IUBMB)
9alpha-copalyl diphosphate = stemar-13-ene + diphosphate [RN:R09115]
Reaction(KEGG)
Substrate
9alpha-copalyl diphosphate [CPD:C11902]
Product
stemar-13-ene [CPD:C18223];
diphosphate [CPD:C00013]
Comment
This diterpene cyclase produces stemar-13-ene, a putative precursor of the rice phytoalexin oryzalexin S. Phytoalexins are diterpenoid secondary metabolites that are involved in the defense mechanism of the plant, and are produced in response to pathogen attack through the perception of elicitor signal molecules such as chitin oligosaccharide, or after exposure to UV irradiation.
History
EC 4.2.3.33 created 2008
Pathway
Diterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K14044  
stemar-13-ene synthase
Genes
OSA: 
4350502(OsDTC2)
OBR: 
Taxonomy
Reference
1  [PMID:8651702]
  Authors
Mohan RS, Yee NK, Coates RM, Ren YY, Stamenkovic P, Mendez I, West CA.
  Title
Biosynthesis of cyclic diterpene hydrocarbons in rice cell suspensions: conversion of 9,10-syn-labda-8(17),13-dienyl diphosphate to 9beta-pimara-7,15-diene and stemar-13-ene.
  Journal
Arch. Biochem. Biophys. 330 (1996) 33-47.
Reference
2  [PMID:15280039]
  Authors
Nemoto T, Cho EM, Okada A, Okada K, Otomo K, Kanno Y, Toyomasu T, Mitsuhashi W, Sassa T, Minami E, Shibuya N, Nishiyama M, Nojiri H, Yamane H.
  Title
Stemar-13-ene synthase, a diterpene cyclase involved in the biosynthesis of the phytoalexin oryzalexin S in rice.
  Journal
FEBS. Lett. 571 (2004) 182-6.
  Sequence
[osa:4350502]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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