KEGG   ENZYME: 4.2.3.35Help
Entry
EC 4.2.3.35                 Enzyme                                 

Name
syn-pimara-7,15-diene synthase;
9beta-pimara-7,15-diene synthase;
OsDTS2;
OsKS4
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming)
Reaction(IUBMB)
9alpha-copalyl diphosphate = 9beta-pimara-7,15-diene + diphosphate [RN:R09117]
Reaction(KEGG)
Substrate
9alpha-copalyl diphosphate [CPD:C11902]
Product
9beta-pimara-7,15-diene [CPD:C18225];
diphosphate [CPD:C00013]
Comment
This enzyme is a class I terpene synthase [1]. 9beta-Pimara-7,15-diene is a precursor of momilactones A and B, rice diterpenoid phytoalexins that are produced in response to attack (by a pathogen, elicitor or UV irradiation) and are involved in the defense mechanism of the plant. Momilactone B can also act as an allochemical, being constitutively produced in the root of the plant and secreted to the rhizosphere where it suppresses the growth of neighbouring plants and soil microorganisms [1].
History
EC 4.2.3.35 created 2008
Pathway
Diterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K14046  
syn-pimara-7,15-diene synthase
Genes
OSA: 
4335094(DTS2)
DOSA: 
Os04t0179700-01(Os04g0179700)
Taxonomy
Reference
1  [PMID:15299118]
  Authors
Wilderman PR, Xu M, Jin Y, Coates RM, Peters RJ.
  Title
Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis.
  Journal
Plant. Physiol. 135 (2004) 2098-105.
  Sequence
Reference
2  [PMID:15388982]
  Authors
Otomo K, Kanno Y, Motegi A, Kenmoku H, Yamane H, Mitsuhashi W, Oikawa H, Toshima H, Itoh H, Matsuoka M, Sassa T, Toyomasu T.
  Title
Diterpene cyclases responsible for the biosynthesis of phytoalexins, momilactones A, B, and oryzalexins A-F in rice.
  Journal
Biosci. Biotechnol. Biochem. 68 (2004) 2001-6.
  Sequence
[osa:4335094]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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