KEGG   ENZYME: 4.2.3.40Help
Entry
EC 4.2.3.40                 Enzyme                                 

Name
(Z)-gamma-bisabolene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate [RN:R09620]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(Z)-gamma-bisabolene [CPD:C16814];
diphosphate [CPD:C00013]
Comment
This sesquiterpenoid enzyme is constitutively expressed in the root, hydathodes and stigma of the plant Arabidopsis thaliana. If the leaves of the plant are wounded, e.g. by cutting, the enzyme is also induced close to the wound site. The sesquiterpenoids (E)-nerolidol and alpha-bisabolol are also produced by this enzyme as minor products.
History
EC 4.2.3.40 created 2009
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15795  
(Z)-gamma-bisabolene synthase
Genes
ATH: 
AT4G13280(TPS12) AT4G13300(TPS13)
ALY: 
Taxonomy
Reference
1  [PMID:16297850]
  Authors
Ro DK, Ehlting J, Keeling CI, Lin R, Mattheus N, Bohlmann J
  Title
Microarray expression profiling and functional characterization of AtTPS genes: duplicated Arabidopsis thaliana sesquiterpene synthase genes At4g13280 and At4g13300 encode root-specific and wound-inducible (Z)-gamma-bisabolene synthases.
  Journal
Arch. Biochem. Biophys. 448 (2006) 104-16.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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