KEGG   ENZYME: 4.2.3.45Help
Entry
EC 4.2.3.45                 Enzyme                                 

Name
phyllocladan-16alpha-ol synthase;
PaDC1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(+)-copalyl-diphosphate diphosphate-lyase (phyllocladan-16alpha-ol-forming)
Reaction(IUBMB)
(+)-copalyl diphosphate + H2O = phyllocladan-16alpha-ol + diphosphate [RN:R09686]
Reaction(KEGG)
Substrate
(+)-copalyl diphosphate [CPD:C11901];
H2O [CPD:C00001]
Product
phyllocladan-16alpha-ol [CPD:C19817];
diphosphate [CPD:C00013]
Comment
The adjacent gene PaDC2 codes EC 5.5.1.12 copalyl diphosphate synthase.
History
EC 4.2.3.45 created 2009
Pathway
Diterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K20514  
phyllocladan-16alpha-ol/copalyl diphosphate synthase
Reference
1  [PMID:18391465]
  Authors
Toyomasu T, Niida R, Kenmoku H, Kanno Y, Miura S, Nakano C, Shiono Y, Mitsuhashi W, Toshima H, Oikawa H, Hoshino T, Dairi T, Kato N, Sassa T
  Title
Identification of diterpene biosynthetic gene clusters and functional analysis of labdane-related diterpene cyclases in Phomopsis amygdali.
  Journal
Biosci. Biotechnol. Biochem. 72 (2008) 1038-47.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system