Entry |
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Name |
(3S,6E)-nerolidol synthase;
(E)-nerolidol synthase;
nerolidol synthase;
(3S)-(E)-nerolidol synthase;
FaNES1
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Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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Sysname |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3S,6E)-nerolidol-forming]
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Reaction(IUBMB) |
(2E,6E)-farnesyl diphosphate + H2O = (3S,6E)-nerolidol + diphosphate [RN: R08374]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores [2]. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants.
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History |
EC 4.2.3.48 created 2010
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Pathway |
ec00909 | Sesquiterpenoid and triterpenoid biosynthesis |
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Orthology |
K14175 | (3S,6E)-nerolidol synthase |
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Genes |
» show all
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Reference |
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Authors |
Aharoni A, Giri AP, Verstappen FW, Bertea CM, Sevenier R, Sun Z, Jongsma MA, Schwab W, Bouwmeester HJ |
Title |
Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species. |
Journal |
Plant. Cell. 16 (2004) 3110-31. |
Reference |
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Authors |
Bouwmeester HJ, Verstappen FW, Posthumus MA, Dicke M |
Title |
Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis. |
Journal |
Plant. Physiol. 121 (1999) 173-80. |
Reference |
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Authors |
Degenhardt J, Gershenzon J |
Title |
Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis. |
Journal |
Planta. 210 (2000) 815-22. |
Reference |
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Authors |
Arimura G, Garms S, Maffei M, Bossi S, Schulze B, Leitner M, Mithofer A, Boland W |
Title |
Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. |
Journal |
Planta. 227 (2008) 453-64. |
Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: | 4.2.3.48 |
ExPASy - ENZYME nomenclature database: | 4.2.3.48 |
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