KEGG   ENZYME: 4.2.3.49Help
Entry
EC 4.2.3.49                 Enzyme                                 

Name
(3R,6E)-nerolidol synthase;
terpene synthase 1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3R,6E)-nerolidol-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = (3R,6E)-nerolidol + diphosphate [RN:R09618]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448];
H2O [CPD:C00001]
Product
(3R,6E)-nerolidol [CPD:C19746];
diphosphate [CPD:C00013]
Comment
The enzyme catalyses a step in the formation of (3E)-4,8-dimethylnona-1,3,7-triene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores [1]. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants.
History
EC 4.2.3.49 created 2010
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15793  
acyclic sesquiterpene synthase
Genes
BDI: 
SBI: 
SORBI_06g028210(SORBIDRAFT_06g028210)
ZMA: 
541974(tps1)
SITA: 
Taxonomy
Reference
1  [PMID:12481088]
  Authors
Schnee C, Kollner TG, Gershenzon J, Degenhardt J
  Title
The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
  Journal
Plant. Physiol. 130 (2002) 2049-60.
  Sequence
[zma:541974]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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