KEGG   ENZYME: 4.2.3.69Help
Entry
EC 4.2.3.69                 Enzyme                                 

Name
(+)-alpha-barbatene synthase;
AtBS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-alpha-barbatene-forming]
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (+)-alpha-barbatene + diphosphate [RN:R09614]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(+)-alpha-barbatene [CPD:C19740];
diphosphate [CPD:C00013]
Comment
The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% alpha-barbatene, 17.8% thujopsene (cf. EC 4.2.3.79, thujopsene synthase) and 9.9% beta-chamigrene (cf. EC 4.2.3.78, beta-chamigrene synthase) [1] plus traces of other sesquiterpenoids [2].
History
EC 4.2.3.69 created 2011, modified 2012
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15799  
(+)-alpha-barbatene/beta-chamigrene/thujopsene synthase
Genes
ATH: 
ALY: 
CRB: 
CSAT: 
EUS: 
BRP: 
BNA: 
BOE: 
Taxonomy
Reference
1  [PMID:15965019]
  Authors
Wu S, Schoenbeck MA, Greenhagen BT, Takahashi S, Lee S, Coates RM, Chappell J
  Title
Surrogate splicing for functional analysis of sesquiterpene synthase genes.
  Journal
Plant. Physiol. 138 (2005) 1322-33.
  Sequence
[ath:AT5G44630]
Reference
2  [PMID:15918888]
  Authors
Tholl D, Chen F, Petri J, Gershenzon J, Pichersky E
  Title
Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers.
  Journal
Plant. J. 42 (2005) 757-71.
  Sequence
[ath:AT5G44630]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
DBGET integrated database retrieval system