KEGG   ENZYME: 4.2.3.78Help
Entry
EC 4.2.3.78                 Enzyme                                 

Name
beta-chamigrene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-beta-chamigrene-forming)
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate [RN:R10598]
Reaction(KEGG)
Substrate
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Product
(+)-beta-chamigrene [CPD:C19908];
diphosphate [CPD:C00013]
Comment
The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% (+)-alpha-barbatene, 17.8% (+)-thujopsene and 9.9% (+)-beta-chamigrene [1] plus traces of other sesquiterpenoids [2]. See EC 4.2.3.69 (+)-alpha-barbatene synthase, and EC 4.2.3.79 thujopsene synthase.
History
EC 4.2.3.78 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15799  
(+)-alpha-barbatene/beta-chamigrene/thujopsene synthase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
Taxonomy
Reference
1  [PMID:15965019]
  Authors
Wu S, Schoenbeck MA, Greenhagen BT, Takahashi S, Lee S, Coates RM, Chappell J
  Title
Surrogate splicing for functional analysis of sesquiterpene synthase genes.
  Journal
Plant. Physiol. 138 (2005) 1322-33.
  Sequence
[ath:AT5G44630]
Reference
2  [PMID:15918888]
  Authors
Tholl D, Chen F, Petri J, Gershenzon J, Pichersky E
  Title
Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers.
  Journal
Plant. J. 42 (2005) 757-71.
  Sequence
[ath:AT5G44630]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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