KEGG   ENZYME: 4.2.99.22Help
Entry
EC 4.2.99.22                Enzyme                                 

Name
tuliposide A-converting enzyme;
tuliposide-converting enzyme;
6-O-(4'-hydroxy-2'-methylenebutyryl)-D-glucose acyltransferase (lactone-forming);
TCA;
TCEA
Class
Lyases;
Carbon-oxygen lyases;
Other carbon-oxygen lyases
BRITE hierarchy
Sysname
6-tuliposide A D-glucose-lyase (tulipalin A forming)
Reaction(IUBMB)
6-tuliposide A = tulipalin A + D-glucose [RN:R10494]
Reaction(KEGG)
Substrate
6-tuliposide A [CPD:C20577]
Product
tulipalin A [CPD:C20578];
D-glucose [CPD:C00031]
Comment
Isolated from the plant Tulipa gesneriana (tulip). The reaction is an intramolecular transesterification producing the lactone. The enzyme also has a weak activity with 6-tuliposide B and 6-O-benzoyl-D-glucose.
History
EC 4.2.99.22 created 2013
Orthology
K20506  
tuliposide A-converting enzyme
Genes
PDA: 
EGU: 
MUS: 
Taxonomy
Reference
1  [PMID:19661715]
  Authors
Kato Y, Shoji K, Ubukata M, Shigetomi K, Sato Y, Nakajima N, Ogita S
  Title
Purification and characterization of a tuliposide-converting enzyme from bulbs of Tulipa gesneriana.
  Journal
Biosci. Biotechnol. Biochem. 73 (2009) 1895-7.
Reference
2  [PMID:22474185]
  Authors
Nomura T, Ogita S, Kato Y
  Title
A novel lactone-forming carboxylesterase: molecular identification of a tuliposide A-converting enzyme in tulip.
  Journal
Plant. Physiol. 159 (2012) 565-78.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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