KEGG   ENZYME: 4.3.1.14Help
Entry
EC 4.3.1.14                 Enzyme                                 

Name
3-aminobutyryl-CoA ammonia-lyase;
L-3-aminobutyryl-CoA deaminase;
L-3-aminobutyryl-CoA ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)
Reaction(IUBMB)
L-3-aminobutyryl-CoA = crotonoyl-CoA + NH3 [RN:R03030]
Reaction(KEGG)
Substrate
L-3-aminobutyryl-CoA [CPD:C05231]
Product
crotonoyl-CoA [CPD:C00877];
NH3 [CPD:C00014]
Comment
Hydroxylamine can replace ammonia as a substrate. Crotonoyl-pantetheine can replace crotonoyl-CoA but it is a poorer substrate.
History
EC 4.3.1.14 created 1999
Pathway
ec00310  Lysine degradation
Orthology
K18014  3-aminobutyryl-CoA ammonia-lyase
Genes
RFR: Rfer_3886
AZA: AZKH_1578
AZI: AzCIB_1070
ADE: Adeh_1486
ACP: A2cp1_2469
AFW: Anae109_2346
ANK: AnaeK_2381
MXA: MXAN_4385
MFU: LILAB_30015
MSD: MYSTI_04874
CPAT: CLPA_c31510(kal)
CPAE: CPAST_c31510(kal)
AMT: Amet_0317
AOE: Clos_2598
CPRO: CPRO_06750(kal_1) CPRO_16260(kal_2) CPRO_21580(kal_3) CPRO_21590(kal_4)
CST: CLOST_1385(kal)
STH: STH63
EHL: EHLA_1858
TTE: TTE0718
PUF: UFO1_1642
PFT: JBW_02723
MBJ: KQ51_00860(kal)
MPHL: MPHLCCUG_04684(kal)
ROP: ROP_36710
SALS: SLNWT_5586
SRW: TUE45_01710(kal)
NCA: Noca_2665
KFL: Kfla_3600
TCU: Tcur_2348
MMAR: MODMU_2633
AOI: AORI_4736
AMI: Amir_3398
SESP: BN6_43160
KAL: KALB_4417
ALL: CRK56466
SAQ: Sare_2386
MIL: ML5_5271
ASE: ACPL_2801
ACTN: L083_3929
AFS: AFR_21800
ACTS: ACWT_2745
SNA: Snas_3948
FNU: FN1869
PGI: PG_1067
PGN: PGN_1163
MBAS: ALGA_2254
TLE: Tlet_0225
TME: Tmel_0189
TAF: THA_421
THER: Y592_02085
FNO: Fnod_0210
PMO: Pmob_1077
MARN: LN42_02750
KOL: Kole_0966
NMR: Nmar_0564
 » show all
Taxonomy
Reference
1  [PMID:4420467]
  Authors
Jeng I, Barker HA.
  Title
Purification and properties of l-3-aminobutyryl coenzyme A deaminase from a lysine-fermenting Clostridium.
  Journal
J. Biol. Chem. 249 (1974) 6578-84.
Reference
2  [PMID:7410315]
  Authors
Barker HA, Kahn JM, Chew S.
  Title
Enzymes involved in 3,5-diaminohexanoate degradation by Brevibacterium sp.
  Journal
J. Bacteriol. 143 (1980) 1165-70.
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.14
IUBMB Enzyme Nomenclature: 4.3.1.14
ExPASy - ENZYME nomenclature database: 4.3.1.14
BRENDA, the Enzyme Database: 4.3.1.14
CAS: 55467-41-9

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