KEGG   ENZYME: 4.3.1.14Help
Entry
EC 4.3.1.14                 Enzyme                                 

Name
3-aminobutyryl-CoA ammonia-lyase;
L-3-aminobutyryl-CoA deaminase;
L-3-aminobutyryl-CoA ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)
Reaction(IUBMB)
L-3-aminobutyryl-CoA = crotonoyl-CoA + NH3 [RN:R03030]
Reaction(KEGG)
Substrate
L-3-aminobutyryl-CoA [CPD:C05231]
Product
crotonoyl-CoA [CPD:C00877];
NH3 [CPD:C00014]
Comment
Hydroxylamine can replace ammonia as a substrate. Crotonoyl-pantetheine can replace crotonoyl-CoA but it is a poorer substrate.
History
EC 4.3.1.14 created 1999
Pathway
Lysine degradation
Orthology
K18014  
3-aminobutyryl-CoA ammonia-lyase
Genes
RFR: 
AZA: 
ADE: 
ACP: 
AFW: 
ANK: 
MXA: 
MFU: 
MSD: 
CCX: 
SUR: 
CTET: 
CBN: 
CLS: 
AMT: 
AOE: 
CST: 
STH: 
DAI: 
BPRL: 
TTE: 
TWI: 
NTH: 
HPK: 
PUF: 
MBJ: 
NCY: 
RHA: 
ROP: 
ROA: 
AAU: 
ICA: 
NCA: 
KFL: 
TCU: 
MMAR: 
AOI: 
AJA: 
AMI: 
SESP: 
KAL: 
STP: 
SAQ: 
MAU: 
MIL: 
VMA: 
AMS: 
ASE: 
ACTN: 
AFS: 
SNA: 
FNU: 
FNC: 
FUS: 
BACC: 
PGI: 
PGN: 
PGT: 
PAH: 
OSP: 
TLE: 
TME: 
TAF: 
FNO: 
FPE: 
PMO: 
KOL: 
MPZ: 
MPG: 
NMR: 
 » show all
Taxonomy
Reference
1  [PMID:4420467]
  Authors
Jeng I, Barker HA.
  Title
Purification and properties of l-3-aminobutyryl coenzyme A deaminase from a lysine-fermenting Clostridium.
  Journal
J. Biol. Chem. 249 (1974) 6578-84.
Reference
2  [PMID:7410315]
  Authors
Barker HA, Kahn JM, Chew S.
  Title
Enzymes involved in 3,5-diaminohexanoate degradation by Brevibacterium sp.
  Journal
J. Bacteriol. 143 (1980) 1165-70.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
55467-41-9

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