KEGG   ENZYME: 4.3.1.20Help
Entry
EC 4.3.1.20                 Enzyme                                 
Name
erythro-3-hydroxy-L-aspartate ammonia-lyase;
erythro-beta-hydroxyaspartate dehydratase;
erythro-3-hydroxyaspartate dehydratase;
erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating);
erythro-3-hydroxy-Ls-aspartate ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
erythro-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)
Reaction(IUBMB)
erythro-3-hydroxy-L-aspartate = oxaloacetate + ammonia [RN:R00347]
Reaction(KEGG)
R00347;
(other) R06131
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Substrate
erythro-3-hydroxy-L-aspartate [CPD:C03961]
Product
oxaloacetate [CPD:C00036];
ammonia [CPD:C00014]
Comment
A pyridoxal-phosphate protein. The enzyme, which was characterized from the bacterium Paracoccus denitrificans NCIMB 8944, is highly specific for the L-isomer of erythro-3-hydroxyaspartate. Different from EC 4.3.1.16, threo-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.27, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, and Ca2+.
Reference
1  [PMID:16749162]
  Authors
Gibbs RG, Morris JG.
  Title
Purification and properties of erythro-beta-hydroxyasparate dehydratase from Micrococcus denitrificans.
  Journal
Biochem. J. 97 (1965) 547-54.
  Organism
Micrococcus denitrificans
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37290-74-7
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