KEGG   ENZYME: 4.3.3.4Help
Entry
EC 4.3.3.4                  Enzyme                                 

Name
deacetylipecoside synthase;
deacetylipecoside dopamine-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Amine-lyases
BRITE hierarchy
Sysname
deacetylipecoside dopamine-lyase (secologanin-forming)
Reaction(IUBMB)
deacetylipecoside + H2O = dopamine + secologanin [RN:R05749]
Reaction(KEGG)
Substrate
deacetylipecoside [CPD:C07307];
H2O [CPD:C00001]
Product
dopamine [CPD:C03758];
secologanin [CPD:C01852]
Comment
The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC 4.3.3.3 deacetylisoipecoside synthase. The product is rapidly converted to demethylalangiside.
History
EC 4.3.3.4 created 2000
Pathway
Isoquinoline alkaloid biosynthesis
Reference
1
  Authors
DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H.
  Title
Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii.
  Journal
Phytochemistry 45 (1997) 477-484.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
192827-93-3

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