KEGG   ENZYME: 4.4.1.14Help
Entry
EC 4.4.1.14                 Enzyme                                 

Name
1-aminocyclopropane-1-carboxylate synthase;
1-aminocyclopropanecarboxylate synthase;
1-aminocyclopropane-1-carboxylic acid synthase;
1-aminocyclopropane-1-carboxylate synthetase;
aminocyclopropanecarboxylic acid synthase;
aminocyclopropanecarboxylate synthase;
ACC synthase;
S-adenosyl-L-methionine methylthioadenosine-lyase
Class
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)
Reaction(IUBMB)
S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine [RN:R00179]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019]
Product
1-aminocyclopropane-1-carboxylate [CPD:C01234];
methylthioadenosine [CPD:C00170]
Comment
A pyridoxal-phosphate protein. The enzyme catalyses an alpha,gamma-elimination.
History
EC 4.4.1.14 created 1984
Pathway
Cysteine and methionine metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K01762  
1-aminocyclopropane-1-carboxylate synthase
K20772  
1-aminocyclopropane-1-carboxylate synthase 1/2/6
Genes
ATH: 
AT1G01480(ACS2) AT2G22810(ACS4) AT3G49700(ACS9) AT3G61510(ACS1) AT4G08040(ACS11) AT4G11280(ACS6) AT4G26200(ACS7) AT4G37770(ACS8) AT5G65800(ACS5)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
GHI: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
CCAJ: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0243559.1(Lj0g3v0243559.1) Lj1g3v1781060.1(Lj1g3v1781060.1) Lj1g3v1781070.1(Lj1g3v1781070.1) Lj1g3v2766570.1(Lj1g3v2766570.1) Lj2g3v0909590.1(Lj2g3v0909590.1) Lj2g3v1982940.1(Lj2g3v1982940.1) Lj2g3v2051190.1(Lj2g3v2051190.1) Lj4g3v0706600.1(Lj4g3v0706600.1) Lj4g3v2990130.1(Lj4g3v2990130.1) Lj4g3v3017360.1(Lj4g3v3017360.1)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
ZJU: 
CSV: 
CMO: 
103484881 103488536(ACS11) 103492295(ACS-7) 103493143(CMe-ACS2) 103497687(CMe-ACS1)
RCU: 
JCU: 
POP: 
POPTR_0001s09850g(POPTRDRAFT_815069) POPTR_0002s11460g(POPTRDRAFT_754872) POPTR_0002s16530g(POPTRDRAFT_830388) POPTR_0003s132201(POPTRDRAFT_757558) POPTR_0006s15410g(POPTRDRAFT_762657) POPTR_0007s14640g(POPTRDRAFT_803014) POPTR_0014s01300g(POPTRDRAFT_572004) POPTR_0018s06960g
VVI: 
SLY: 
101246650(LE-ACS1B) 101258054 101258353 101260914 101265900 101267421 543621(ACS7B) 544028(ACS1A) 606300(ACS5) 606301(ACS8) 606302(ACS6) 606304(ACS2) 778292(ACS3) 778356(ACS4) 780563(ACC4)
SPEN: 
SOT: 
CANN: 
NTA: 
INI: 
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0192900-00(Os01g0192900) Os03t0727600-01(Os03g0727600) Os04t0578000-01(Os04g0578000) Os05t0196600-00(Os05g0196600) Os05t0319200-00(Os05g0319200)
OBR: 
BDI: 
ATS: 
SBI: 
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
MPP: 
CSL: 
CVR: 
CME: 
DFA: 
FCY: 
GTT: 
SLD: 
LMOI: 
 » show all
Taxonomy
Reference
1
  Authors
Boller, T., Herner, R.C. and Kende, H.
  Title
Assay for and enzymatic formation of an ethylene precursor, 1-aminocyclopropane-1-carboxylic acid.
  Journal
Planta 145 (1979) 293-303.
Reference
2  [PMID:507845]
  Authors
Yu YB, Adams DO, Yang SF.
  Title
1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene biosynthesis.
  Journal
Arch. Biochem. Biophys. 198 (1979) 280-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
72506-68-4

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