KEGG   ENZYME: 4.6.1.2Help
Entry
EC 4.6.1.2                  Enzyme                                 

Name
guanylate cyclase;
guanylyl cyclase;
guanyl cyclase;
GTP diphosphate-lyase (cyclizing)
Class
Lyases;
Phosphorus-oxygen lyases;
Phosphorus-oxygen lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)
Reaction(IUBMB)
GTP = 3',5'-cyclic GMP + diphosphate [RN:R00434]
Reaction(KEGG)
Substrate
GTP [CPD:C00044]
Product
3',5'-cyclic GMP [CPD:C00942];
diphosphate [CPD:C00013]
Comment
Also acts on ITP and dGTP.
History
EC 4.6.1.2 created 1972
Pathway
Purine metabolism
Orthology
K01769  
guanylate cyclase, other
K12318  
guanylate cyclase soluble subunit alpha
K12319  
guanylate cyclase soluble subunit beta
K12320  
heat-stable enterotoxin receptor
K12321  
guanylate cyclase 2D/E
K12322  
guanylate cyclase 2F
K12323  
atrial natriuretic peptide receptor A
K12324  
atrial natriuretic peptide receptor B
K22600  
guanylate cyclase 2G
Genes
HSA: 
2977(GUCY1A2) 2982(GUCY1A1) 2983(GUCY1B1) 2984(GUCY2C) 2986(GUCY2F) 3000(GUCY2D) 4881(NPR1) 4882(NPR2)
PTR: 
100608597(GUCY1A1) 451435 452727 457329(NPR1) 461565(GUCY1B1) 465084(NPR2) 465806(GUCY2F) 466203 466769(GUCY1A2) 473375(GUCY2C) 750641(GUCY2D)
PPS: 
100975209(GUCY2C) 100976525(GUCY2D) 100978077 100980358 100983770(NPR1) 100984343(GUCY2F) 100984704(GUCY1B3) 100985928(GUCY1A3) 100987635(GUCY1A2) 100991030(NPR2)
GGO: 
101128425 101131617(NPR1) 101134962(GUCY2F) 101138030(GUCY2C) 101139175(GUCY1A3) 101140749(GUCY2D) 101141380(GUCY1B3) 101145840(NPR2) 101146114(GUCY1A2) 101146677 109024998
PON: 
100172608(GUCY1A1) 100434873(GUCY1B1) 100437411(NPR2) 100442459(NPR1) 100443214(GUCY2D) 100445008 100445361(GUCY1A2) 100451211(GUCY2F) 100460177 100460918(GUCY2C)
NLE: 
100581660(GUCY1A3) 100583335(GUCY1B3) 100585866(GUCY2D) 100587777 100588933(GUCY2F) 100592351(GUCY1A2) 100594944(GUCY2C) 100595720(NPR2) 100600502 100601694(NPR1) 100605363
MCC: 
100423770 100424944(GUCY1B3) 695750(NPR2) 699191(GUCY2C) 699365(GUCY1A3) 704485(GUCY2F) 706615(GUCY1A2) 715598(NPR1) 716734(GUCY2D)
MCF: 
101866366(GUCY1A3) 101866588(GUCY1B3) 102120445 102127299(GUCY1A2) 102129950(GUCY2F) 102130850(GUCY2C) 102136166 102136908(NPR2) 102143449(NPR1) 102146353(GUCY2D)
CSAB: 
103214549 103216524 103218671(GUCY2C) 103219213(NPR2) 103223952(NPR1) 103232475(GUCY2F) 103236428(GUCY1A3) 103236429(GUCY1B3) 103242335(GUCY2D) 103248387(GUCY1A2)
RRO: 
104655958 104658100(GUCY1A3) 104658102(GUCY1B3) 104661674(GUCY2D) 104661940(GUCY1A2) 104662724 104663522(NPR1) 104664442 104666399(GUCY2C) 104672382(NPR2) 104674410(GUCY2F)
RBB: 
108513181(GUCY1A2) 108514277(GUCY2D) 108517394 108518838(NPR1) 108518991(NPR2) 108527520 108529025(GUCY1B3) 108529026(GUCY1A3) 108530463(GUCY2C) 108530715 108531521(GUCY2F) 108538805
CJC: 
100387768(GUCY1A2) 100390920 100395297(GUCY1B3) 100396127(GUCY1A3) 100396371(NPR1) 100406002(GUCY2C) 100410561(GUCY2F) 100410630(NPR2) 100412242(GUCY2D)
SBQ: 
101027848 101031889(GUCY2D) 101035077(GUCY2F) 101037653 101038981(GUCY2C) 101040246(GUCY1B3) 101040779(GUCY1A3) 101040955(GUCY1A2) 101044584(NPR1) 101049666(NPR2)
MMU: 
14917(Gucy2c) 14918(Gucy2d) 14919(Gucy2e) 18160(Npr1) 230103(Npr2) 234889(Gucy1a2) 239134(Gucy1b2) 245650(Gucy2f) 54195(Gucy1b1) 60596(Gucy1a1) 73707(Gucy2g)
RNO: 
113911(Gucy2d) 116556(Gucy2f) 116564(Npr2) 245708(Gucy2g) 24603(Npr1) 25202(Gucy1b3) 25206(Gucy1b2) 25711(Gucy2c) 497757(Gucy1a3) 66012(Gucy1a2) 79222(Gucy2e)
CGE: 
NGI: 
103727194 103731324(Gucy1a2) 103731771 103741534(Npr2) 103743062 103750026(Gucy2f) 103751001(Gucy1a3) 103751002(Gucy1b3) 103751781(Npr1) 103752104(Gucy2d) 103752330(Gucy2c)
HGL: 
101697777(Gucy2d) 101702803(Gucy1a2) 101707903(Gucy2f) 101712380(Npr2) 101712487(Gucy1a3) 101713282 101714641(Npr1) 101717731 101720874(Gucy2c) 101724888(Gucy1b3) 101726611
CCAN: 
109675363 109676102(Gucy1a3) 109681095 109683638(Gucy1b3) 109684240(Gucy1a2) 109688055(Npr1) 109688562 109693375(Npr2) 109693913(Gucy2d) 109696930(Gucy2c) 109698643(Gucy2f)
OCU: 
100008740(GUCY2C) 100340698(GUCY2F) 100343663(NPR1) 100344092 100344095(GUCY2D) 100349851(GUCY1B3) 100350099(GUCY1A3) 100356598(NPR2) 100357621(GUCY1A2)
TUP: 
102469297(GUCY1A2) 102478622 102482734(NPR1) 102483882(GUCY1A3) 102485635 102488370(GUCY1B3) 102494681 102495739(GUCY2C) 102496410(GUCY2D) 102502023(NPR2)
CFA: 
403863(GUCY2D) 474762(NPR2) 479455(GUCY1A2) 481016(GUCY2F) 482663(GUCY1A3) 485179 485435 486671(GUCY2C) 490455(NPR1) 553102(GUCY1B3)
AML: 
100464538(GUCY1A2) 100468070 100468576(GUCY2C) 100469110(GUCY2F) 100472601(NPR2) 100472771(NPR1) 100472992 100476540 100480095(GUCY2D) 100481364(GUCY1B3) 100483617(GUCY1A3)
UMR: 
103658044(GUCY1A3) 103658045(GUCY1B3) 103659237 103660485(GUCY2D) 103662433(GUCY1A2) 103667090(NPR2) 103668723(NPR1) 103677696 103677772(GUCY2C) 103678130 103679746(GUCY2F)
ORO: 
101365290 101367891 101369879(GUCY1A2) 101371476(GUCY2F) 101377149 101380641(GUCY1B3) 101381618(GUCY1A3) 101382463(GUCY2C) 101383563(GUCY2D) 101384059(NPR1) 101385033(NPR2)
FCA: 
101080682(NPR1) 101089435(GUCY1B1) 101090242(GUCY2F) 101094301(NPR2) 101095109(GUCY2C) 101098377(GUCY1A1) 101098598 101099494(GUCY1A2) 101099582 101101009(GUCY2D) 101101087
PTG: 
102949070(NPR2) 102949926(GUCY2F) 102955254(NPR1) 102956040(GUCY1A2) 102960287(GUCY2D) 102963095(GUCY2C) 102963951(GUCY1B3) 102969669(GUCY1A3) 102970885 102971963 102972759
AJU: 
106965660(GUCY2C) 106972445(GUCY2D) 106972647 106973153(GUCY2F) 106976443 106981295(NPR2) 106982460(GUCY1B3) 106982463(GUCY1A3) 106983909(GUCY1A2) 106984748 106987270(NPR1)
BTA: 
100295021(GUCY2E) 107131161 281216(GUCY1A3) 281357(NPR2) 282244(GUCY2C) 282245(GUCY2D) 282246(GUCY2F) 282433(GUCY1B3) 533048(NPR1) 613600(GUCY1A2)
BOM: 
102267198 102274513(GUCY2F) 102278070(NPR2) 102279810(NPR1) 102280817(GUCY1A2) 102281141(GUCY2D) 102281834(GUCY1A3) 102282106(GUCY1B3) 102284444(GUCY2C) 102285947
BIU: 
109554550(NPR1) 109555058(GUCY2F) 109559629(GUCY2C) 109563021(NPR2) 109566993 109570022(GUCY1A2) 109570892(GUCY1B3) 109570893 109571318(GUCY1A3) 109574462(GUCY2D)
PHD: 
102316801(NPR2) 102319851(GUCY2F) 102325669 102326726(GUCY2D) 102328814(GUCY1A2) 102329923(NPR1) 102332578(GUCY1B3) 102341269 102341664(GUCY2C) 102343775
CHX: 
100861577(NPR2) 102169406(GUCY1B3) 102169418(GUCY2D) 102169692(GUCY1A3) 102180380(GUCY2F) 102182418 102184168(GUCY1A2) 102186447(NPR1) 108636048(GUCY2C)
OAS: 
101104339(GUCY1A2) 101106088 101108212(GUCY2C) 101109482 101110000(GUCY1A3) 101112033(GUCY2F) 101112950(NPR2) 101117809 101120932(GUCY2D) 101123436(NPR1) 106990802 443165(GUCY1B3)
SSC: 
100153508(NPR1) 100512698(NPR2) 100522091(GUCY1A2) 100523457 100625149 100625536(GUCY2D) 100737736(GUCY2F) 397193(GUCY2C) 444999(GUCY1B3) 553100(GUCY1A3)
CFR: 
102503713(GUCY2D) 102507709(NPR2) 102508002(GUCY1A3) 102508234(GUCY1B3) 102509037 102510749 102514869(NPR1) 102516411(GUCY2C) 102522209 102523651(GUCY1A2)
CDK: 
105089423(NPR1) 105091014 105093187(GUCY2F) 105096521(GUCY2C) 105098241 105099193(GUCY1A2) 105101179(GUCY1B3) 105101181(GUCY1A3) 105102284(NPR2) 105102998(GUCY2D)
BACU: 
102998599(GUCY2F) 103002685 103002831(NPR2) 103006662(GUCY2C) 103006879(NPR1) 103007177(GUCY1A2) 103016360(GUCY2D) 103020709(GUCY1B3) 103020943 103020991
LVE: 
103069064 103069938(GUCY1A2) 103070106(GUCY2D) 103071136(GUCY2F) 103075302 103075578(GUCY1B3) 103081407(GUCY2C) 103087466(NPR2) 103088382(NPR1)
OOR: 
101269588(GUCY2F) 101271659 101273275(NPR2) 101274865 101275975(GUCY1A2) 101279031(GUCY1B3) 101279277(GUCY1A3) 101282297(GUCY2D) 101284028(GUCY2C) 101284510 101288628(NPR1)
ECB: 
100054420 100054502(GUCY2F) 100055416(NPR2) 100061959(NPR1) 100063810(GUCY2C) 100068630 100069474(GUCY1A2) 100069551(GUCY1B1) 100069573(GUCY1A1) 100073037(GUCY2D)
EPZ: 
EAI: 
106826729(GUCY2C) 106832984(GUCY1A3) 106833011(GUCY1B3) 106837558 106837662(GUCY1A2) 106837722 106839735(GUCY2F) 106840416 106844230(GUCY2D) 106846257(NPR1) 106846972(NPR2)
MYB: 
102238967(NPR2) 102241126(GUCY2F) 102242149 102243506(GUCY2D) 102247939(GUCY2C) 102249825(NPR1) 102250379(GUCY1B3) 102250686(GUCY1A3) 102258634 102260196(GUCY1A2) 102261219
MYD: 
102751706(GUCY2D) 102755806(NPR1) 102758657 102760543 102764771(GUCY1A3) 102767033(GUCY1A2) 102769452(GUCY1B3) 102771508(NPR2) 102772626(GUCY2C) 102775033
HAI: 
109371447(GUCY1A2) 109373524(NPR1) 109376730(GUCY2F) 109377496(GUCY1A3) 109377497(GUCY1B3) 109383130(GUCY2C) 109384884 109387114 109393761(NPR2) 109395113(GUCY2D) 109395130
RSS: 
109435417(NPR1) 109444060 109446046(NPR2) 109448164(GUCY1B3) 109448176(GUCY1A3) 109454238(GUCY2C) 109454412(GUCY2D) 109455902(GUCY1A2)
PALE: 
102878600(GUCY2F) 102879793(NPR1) 102881321 102883474(GUCY2C) 102884807 102885265(NPR2) 102889391 102889502(GUCY1A3) 102889920(GUCY1B3) 102892708(GUCY2D) 102896673(GUCY1A2)
LAV: 
100656347 100662779(GUCY1A2) 100663946(GUCY1A1) 100665374(GUCY1B1) 100670740(GUCY2D) 100670819(GUCY2F) 100671961(NPR1) 100675825(GUCY2C) 100676051 100676492(NPR2)
TMU: 
MDO: 
100014788(GUCY2D) 100016988(GUCY2C) 100017038(GUCY1A3) 100019736(NPR1) 100020156(NPR2) 100024008(GUCY1B3) 100027037(GUCY1A2) 100027754 100028110 100028289
SHR: 
100921433(GUCY2D) 100921526(NPR1) 100925538(GUCY2C) 100928661(GUCY1A1) 100929308(GUCY1A2) 100931427(GUCY1B1) 100932257 100932333(NPR2) 105749254
OAA: 
100074490 100075186(GUCY1A3) 100077965(GUCY1A2) 100079900(GUCY1B3) 100082549 100082922 100087666(NPR2) 100091310(GUCY2C)
GGA: 
100859339(NPR2) 417968(GUCY2C) 419089(GUCY2F) 422407(GUCY1A3) 422408(GUCY1B3) 429128(GUCY1B4) 771678(GUCY1A2)
MGP: 
100539100 100539537(NPR2) 100542159(GUCY1A2) 100544016(GUCY2F) 100547213(GUCY1A3) 100547365(GUCY1B3) 100550786(GUCY2C)
CJO: 
107305835(NPR2) 107308362(GUCY1A2) 107308518(GUCY2F) 107313044(GUCY1B3) 107313055(GUCY1A3) 107313537(GUCY2C) 107318030 107324375(NPR1)
APLA: 
101790692(GUCY1A2) 101796516 101799600(GUCY1A3) 101800833(GUCY2F) 101802157(GUCY2C) 101805092 101805193(GUCY1B3) 106019034
ACYG: 
106029423 106032273(GUCY1A3) 106032278(GUCY1B3) 106036260 106036311(NPR2) 106042382(GUCY2F) 106046052(GUCY2C) 106047549(GUCY1A2) 106049109(NPR1) 106049690
TGU: 
100217644(GUCY1A2) 100223544(GUCY1B3) 100223563(GUCY1A3) 100225337 100227153(NPR2) 100228246(GUCY2C) 100229764(GUCY2F)
GFR: 
102038803(GUCY2F) 102038841 102039158(NPR2) 102042400(GUCY2C) 102043713(GUCY1B3) 102043874(GUCY1A3) 102044723(GUCY1A2)
FAB: 
101807229(NPR2) 101809957 101812872(GUCY1A2) 101814320(GUCY1A3) 101815504(GUCY1B3) 101816039(GUCY2C) 101816994(GUCY2F) 101818523 101822049
PHI: 
102099657(GUCY2F) 102105071 102105257(NPR2) 102106220(GUCY1A3) 102106413(GUCY1B3) 102111535(GUCY2C) 102113474(GUCY1A2) 102114027(GUCY2D) 106628815(NPR1)
PMAJ: 
107198475(NPR2) 107199562 107203218(GUCY1A3) 107203428(GUCY1B3) 107204266(GUCY2C) 107208956 107210410(GUCY1A2) 107210870(GUCY2F) 107214622(NPR1)
CCW: 
104686575(NPR2) 104690109(GUCY1A2) 104690280(GUCY2F) 104693425 104696375(GUCY2C) 104697178(GUCY1A3) 104697179(GUCY1B3)
FPG: 
101913205(GUCY2C) 101914436(GUCY1A2) 101915374(GUCY1B3) 101916520 101916740(NPR2) 101920979 101922339(GUCY1A3) 101924821(GUCY2F)
FCH: 
102046999(GUCY1A3) 102048540(GUCY1B3) 102050145 102051925(NPR2) 102053014(GUCY2C) 102054518 102055553(GUCY2F) 102059430(GUCY1A2)
CLV: 
102086091(GUCY2F) 102090855(GUCY1A3) 102091284 102091873(GUCY1B3) 102095707 102097001 102097143(GUCY1A2) 102098846(NPR2) 102098904(GUCY2C)
EGZ: 
104122981(NPR1) 104124167(GUCY1B3) 104124168(GUCY1A3) 104124743(GUCY2F) 104128541 104130062(GUCY1A2) 104133897(NPR2) 104134274(GUCY2C) 104135463
AAM: 
ASN: 
102368327(NPR2) 102373414(NPR1) 102373559(GUCY2F) 102374400(GUCY2C) 102375187(GUCY2D) 102375853 102383096(GUCY1B3) 102383277(GUCY1A2) 102383335(GUCY1A3) 102385932 106722154
AMJ: 
102558504(GUCY2C) 102559036(GUCY2F) 102561438 102563737 102564997(GUCY2D) 102565558(GUCY1B3) 102569074(GUCY1A3) 102572749 106736703(NPR1) 106737232(GUCY1A2) 106737496
PSS: 
102444148(GUCY2C) 102444454(GUCY1A2) 102446826(GUCY1A3) 102447071(GUCY1B3) 102448215 102451086(GUCY2D) 102451605 102452749
CMY: 
CPIC: 
ACS: 
PVT: 
PBI: 
103052637(NPR2) 103052921(GUCY1A2) 103056579(NPR1) 103057412 103060465 103061127 103062751(GUCY2F) 103063344(GUCY1A3) 103063696 103063891(GUCY1B3) 103064925(GUCY2D) 103067773(GUCY2C)
GJA: 
XLA: 
108695992 108698903(gucy2f.L) 108700543(gucy2f.S) 108703527(gucy2d.S) 108704686 108705075 108706648(gucy1a3.S) 108707622 108709988 108711755(gucy2d.L) 108715011(gucy2c.S) 108717066 108717463 108719605(gucy1b3.L) 378662(gucy2c.L) 397794(xgc-1) 399070(npr1.L) 399350(npr2.S) 432281(gucy1b3.S)
XTR: 
100145454(gucy1a2) 100379900(gucy1b3) 100486678(gucy2c) 100488543(npr2) 100489435 100492092(npr1) 100492820(gucy2f) 100496590(gucy2d) 100496677(gucy1a3) 100496697(gucy1b2)
NPR: 
DRE: 
100150304(gucy1b1) 100330875(gucy1a2) 100331745(npr2) 100333350(gucy2g) 140424(gucy2f) 140425(gc2) 140426(gucy2d) 550420(gucy1a1) 555911(npr1b) 557191(gucy1b2) 560653(npr1a) 568219(si:ch73-139e5.4) 572052(gucy2c)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
100049178(gucy1b1) 100049183(npr2) 100049189(olgc-r1) 100049248(gucy1a2) 100125799(olgc2) 100125818(olgc9) 100125819(olgc7) 100125820(olgc6) 100192404(olgc3) 100216004(olgc-r2) 101172201
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
APLC: 
SKO: 
DME: 
Dmel_CG1470(Gycbeta100B) Dmel_CG14885(Gyc89Da) Dmel_CG14886(Gyc89Db) Dmel_CG1912(Gycalpha99B) Dmel_CG31183(CG31183) Dmel_CG3216 Dmel_CG33114(Gyc32E) Dmel_CG34357(CG34357) Dmel_CG4154(Gyc88E) Dmel_CG42636(Gyc76C) Dmel_CG42637(CG42637)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD12253(Dsim_GD12253) Dsimw501_GD18990(Dsim_GD18990) Dsimw501_GD19104(Dsim_GD19104) Dsimw501_GD19105(Dsim_GD19105) Dsimw501_GD19673(Dsim_GD19673) Dsimw501_GD20320(Dsim_GD20320) Dsimw501_GD21450(Dsim_GD21450) Dsimw501_GD21561(Dsim_GD21561) Dsimw501_GD22188(Dsim_GD22188) Dsimw501_GD25238(Dsim_GD25238)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
408879(sGC-alpha1) 408880(Gycbeta1) 409422(GB11811) 411635(sGCbeta-3) 413274(GB10150) 724571 724603(GB12179) 726069
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
DPA: 
NVL: 
BMOR: 
DPL: 
PMAC: 
PRAP: 
PXY: 
API: 
DNX: 
PHU: 
ZNE: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CELE_AH6.1(gcy-1) CELE_C06B3.8(gcy-32) CELE_C46E1.2(gcy-36) CELE_C49H3.1(gcy-8) CELE_F08B1.2(gcy-12) CELE_F21H7.9(gcy-20) CELE_F22E5.3(gcy-21) CELE_F57F5.2(gcy-33) CELE_M04G12.3(gcy-34) CELE_R134.1(gcy-3) CELE_R134.2(gcy-2) CELE_T01A4.1(gcy-28) CELE_T04D3.4(gcy-35) CELE_T07D1.1(gcy-31) CELE_T26C12.4(gcy-23) CELE_W03F11.2(gcy-17) CELE_ZC239.7(gcy-15) CELE_ZC412.2(gcy-14) CELE_ZK896.8(gcy-18) CELE_ZK970.6(gcy-5)
CBR: 
CBG02110(Cbr-gcy-31) CBG03898 CBG06726(Cbr-gcy-34) CBG07710 CBG14865(Cbr-gcy-28) CBG20390(Cbr-gcy-35) CBG23350(Cbr-gcy-33)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
EPA: 
ADF: 
HMG: 
TAD: 
AQU: 
CRE: 
VCN: 
MNG: 
MBR: 
SRE: 
ACAN: 
PFA: 
MAL13P1.301(gc-betA)
PKN: 
FCY: 
TPS: 
PSOJ: 
TVA: 
PAT: 
MFA: 
MMB: 
MEH: 
BRA: 
BBT: 
JAN: 
TER: 
 » show all
Taxonomy
Reference
1  [PMID:235291]
  Authors
Garbers DL, Suddath JL, Hardman JG.
  Title
Enzymatic formation of inosine 3',5'-monophosphate and of 2'-deoxyguanosine 3',5'-monophosphate. Inosinate and deoxyguanylate cyclase activity.
  Journal
Biochim. Biophys. Acta. 377 (1975) 174-85.
Reference
2  [PMID:4982201]
  Authors
Hardman JG, Sutherland EW.
  Title
Guanyl cyclase, an enzyme catalyzing the formation of guanosine 3',5'-monophosphate from guanosine trihosphate.
  Journal
J. Biol. Chem. 244 (1969) 6363-70.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9054-75-5

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