KEGG   ENZYME: 5.1.1.21Help
Entry
EC 5.1.1.21                 Enzyme                                 

Name
isoleucine 2-epimerase;
BCAA racemase
Class
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
BRITE hierarchy
Sysname
isoleucine 2-epimerase
Reaction(IUBMB)
L-isoleucine = D-allo-isoleucine [RN:R11078]
Reaction(KEGG)
Substrate
L-isoleucine [CPD:C00407]
Product
D-allo-isoleucine [CPD:C21092]
Comment
A pyridoxal phosphate protein. The enzyme, characterized from the bacterium Lactobacillus buchneri, specifically catalyses racemization of nonpolar amino acids at the C-2 position.
History
EC 5.1.1.21 created 2015
Orthology
K20708  
isoleucine 2-epimerase
Genes
LPL: 
lp_1721(gabT)
LPJ: 
LPT: 
LPS: 
LPR: 
LPZ: 
LPB: 
LBH: 
LBN: 
LHO: 
LGN: 
LHI: 
LPX: 
OOE: 
 » show all
Taxonomy
Reference
1  [PMID:24039265]
  Authors
Mutaguchi Y, Ohmori T, Wakamatsu T, Doi K, Ohshima T
  Title
Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species.
  Journal
J. Bacteriol. 195 (2013) 5207-15.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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