KEGG   ENZYME: 5.1.3.11Help
Entry
EC 5.1.3.11                 Enzyme                                 

Name
cellobiose epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
cellobiose 2-epimerase
Reaction(IUBMB)
cellobiose = 4-O-beta-D-glucopyranosyl-D-mannose [RN:R01445 R06245]
Reaction(KEGG)
R01445 R06245(G);
(other) R10810
Show
Substrate
cellobiose [CPD:C00185]
Product
4-O-beta-D-glucopyranosyl-D-mannose [CPD:C02964]
Comment
The enzyme catalyses the interconversion between D-glucose and D-mannose residues at the reducing end of beta-1,4-linked disaccharides by epimerizing the hydroxyl group at the C-2 position of the glucose moiety.
History
EC 5.1.3.11 created 1972
Orthology
K16213  
cellobiose epimerase
Genes
VFU: 
GAG: 
CJA: 
CJA_0243(unk2)
SDE: 
TTU: 
SAGA: 
BCO: 
AXL: 
PJD: 
GYM: 
PPY: 
PPM: 
PPO: 
PPM_4806(rnbP)
PPOL: 
PPQ: 
PPOY: 
PMS: 
PMQ: 
PMW: 
PTA: 
PBD: 
PGM: 
POD: 
PAEN: 
PAEF: 
PAEQ: 
PSTE: 
PAEA: 
PAEE: 
PAEH: 
PAEJ: 
PRI: 
PRIO_2006(bfce)
PPEO: 
TCO: 
CAW: 
CCB: 
CLB: 
CCE: 
ESR: 
ESU: 
CSS: 
CSD: 
EHA: 
RAL: 
RCH: 
RUS: 
FPA: 
CLE: 
RHO: 
RIX: 
RIM: 
COO: 
CPY: 
CSC: 
ATE: 
COB: 
CHD: 
CKI: 
CKN: 
CLC: 
TTM: 
TTO: 
TSH: 
MAS: 
CYN: 
HAU: 
ATM: 
FGI: 
OTE: 
OBT: 
TBE: 
TAZ: 
SSM: 
STA: 
STQ: 
SBU: 
SLR: 
PHM: 
BFR: 
BFS: 
BFG: 
BFB: 
BHL: 
BSA: 
BDO: 
BOA: 
BCEL: 
PDI: 
PPN: 
PBT: 
PRU: 
PDN: 
DOI: 
RMR: 
RMG: 
CPI: 
NKO: 
HHY: 
PHE: 
PSN: 
SHG: 
SCN: 
CMR: 
CAMU: 
DFE: 
SLI: 
SRD: 
LBY: 
RSI: 
EOL: 
FAE: 
PKO: 
RUF: 
RTI: 
FBT: 
FJO: 
ZPR: 
FBC: 
MRO: 
DTH: 
DTU: 
HTU: 
SALI: 
HLR: 
 » show all
Taxonomy
Reference
1  [PMID:6069974]
  Authors
Tyler TR, Leatherwood JM.
  Title
Epimerization of disaccharides by enzyme preparations from Ruminococcus albus.
  Journal
Arch. Biochem. Biophys. 119 (1967) 363-7.
Reference
2  [PMID:18392616]
  Authors
Ito S, Taguchi H, Hamada S, Kawauchi S, Ito H, Senoura T, Watanabe J, Nishimukai M, Ito S, Matsui H
  Title
Enzymatic properties of cellobiose 2-epimerase from Ruminococcus albus and the synthesis of rare oligosaccharides by the enzyme.
  Journal
Appl. Microbiol. Biotechnol. 79 (2008) 433-41.
  Sequence
Reference
3  [PMID:23462136]
  Authors
Fujiwara T, Saburi W, Inoue S, Mori H, Matsui H, Tanaka I, Yao M
  Title
Crystal structure of Ruminococcus albus cellobiose 2-epimerase: structural insights into epimerization of unmodified sugar.
  Journal
FEBS. Lett. 587 (2013) 840-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37318-37-9

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