KEGG   ENZYME: 5.1.3.19Help
Entry
EC 5.1.3.19                 Enzyme                                 

Name
chondroitin-glucuronate 5-epimerase;
polyglucuronate 5-epimerase;
dermatan-sulfate 5-epimerase;
urunosyl C-5 epimerase;
chondroitin D-glucuronosyl 5-epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
chondroitin-D-glucuronate 5-epimerase
Reaction(IUBMB)
chondroitin D-glucuronate = dermatan L-iduronate [RN:R04104]
Reaction(KEGG)
Substrate
chondroitin D-glucuronate
Product
dermatan L-iduronate [CPD:C01490]
Comment
Not identical with EC 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase.
History
EC 5.1.3.19 created 1986
Pathway
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
Metabolic pathways
Orthology
K01794  
chondroitin-glucuronate 5-epimerase
Genes
HSA: 
29940(DSE)
PTR: 
462957(DSE)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
716054(DSE)
MCF: 
CSAB: 
RRO: 
CJC: 
SBQ: 
MMU: 
212898(Dse)
RNO: 
365583(Dse)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
476271(DSE)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
514028(DSE)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
LAV: 
MDO: 
SHR: 
OAA: 
GGA: 
421745(DSE)
MGP: 
CJO: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
GJA: 
XTR: 
DRE: 
568713(dse)
TRU: 
TNG: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
CMK: 
 » show all
Taxonomy
Reference
1  [PMID:7092807]
  Authors
Malmstrom A, Aberg L.
  Title
Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase.
  Journal
Biochem. J. 201 (1982) 489-93.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
70766-66-4

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