KEGG   ENZYME: 5.1.3.26Help
Entry
EC 5.1.3.26                 Enzyme                                 

Name
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase;
GlcNAc-P-P-Und epimerase;
GlcNAc-P-P-Und 4-epimerase;
gne (gene name)
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase
Reaction(IUBMB)
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10554]
Reaction(KEGG)
Substrate
N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C01289]
Product
N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol [CPD:C20620]
Comment
The enzyme is involved in biosynthesis of the repeating tetrasaccharide unit of the O-antigen produced by some Gram-negative bacteria.
History
EC 5.1.3.26 created 2013
Orthology
K19997  
GlcNAc-P-P-Und epimerase
Genes
ECE: 
ECS: 
ECF: 
ETW: 
ELX: 
ECG: 
EOK: 
ELR: 
ECM: 
ECR: 
ECQ: 
ECK: 
ESO: 
ESM: 
ESL: 
ECL: 
SBG: 
YPY: 
YSI: 
YAK: 
SBC: 
PCV: 
ESA: 
CSK: 
CSI: 
CSJ: 
CDM: 
CMJ: 
CFD: 
SPE: 
SRR: 
SRL: 
SRY: 
SRS: 
SRA: 
SMAF: 
SMW: 
SMAR: 
SMAC: 
SLQ: 
SERF: 
SERS: 
SFO: 
EIC: 
ETC: 
HDE: 
HDEF_0179(galE_1)
PANP: 
CNT: 
DSF: 
DTO: 
REI: 
BRAD: 
XAU: 
PHL: 
BVR: 
CAK: 
CHQ: 
RCP: 
PGV: 
DOR: 
DMI: 
MRH: 
BCV: 
PRC: 
FGI: 
OBT: 
CAA: 
TDE: 
TBE: 
TPK: 
TRM: 
SLR: 
FSU: 
FSC: 
GBA: 
BTH: 
BFR: 
BFG: 
BFB: 
BVU: 
BHL: 
BSA: 
BXY: 
BDO: 
BDH: 
BOA: 
OSP: 
PRU: 
EVI: 
FBT: 
EAO: 
EMN: 
ELB: 
VO54_03300(galE_3)
CPB: 
CLI: 
PVI: 
PAA: 
 » show all
Taxonomy
Reference
1  [PMID:19923219]
  Authors
Rush JS, Alaimo C, Robbiani R, Wacker M, Waechter CJ
  Title
A novel epimerase that converts GlcNAc-P-P-undecaprenol to GalNAc-P-P-undecaprenol in Escherichia coli O157.
  Journal
J. Biol. Chem. 285 (2010) 1671-80.
  Sequence
[ece:Z3206]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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