KEGG   ENZYME: 5.1.3.28Help
Entry
EC 5.1.3.28                 Enzyme                                 

Name
UDP-N-acetyl-L-fucosamine synthase;
WbjD;
Cap5G
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase
Reaction(IUBMB)
UDP-2-acetamido-2,6-dideoxy-beta-L-talose = UDP-N-acetyl-beta-L-fucosamine [RN:R10676]
Reaction(KEGG)
Substrate
UDP-2-acetamido-2,6-dideoxy-beta-L-talose [CPD:C20768]
Product
UDP-N-acetyl-beta-L-fucosamine [CPD:C20774]
Comment
Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis.
History
EC 5.1.3.28 created 2014
Reference
1  [PMID:12464616]
  Authors
Kneidinger B, O'Riordan K, Li J, Brisson JR, Lee JC, Lam JS
  Title
Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
  Journal
J. Biol. Chem. 278 (2003) 3615-27.
Reference
2  [PMID:15778500]
  Authors
Mulrooney EF, Poon KK, McNally DJ, Brisson JR, Lam JS
  Title
Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
  Journal
J. Biol. Chem. 280 (2005) 19535-42.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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