KEGG   ENZYME: 5.1.3.31Help
Entry
EC 5.1.3.31                 Enzyme                                 

Name
D-tagatose 3-epimerase;
L-ribulose 3-epimerase;
ketose 3-epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
D-tagatose 3-epimerase
Reaction(IUBMB)
(1) D-tagatose = D-sorbose [RN:R10818];
(2) D-psicose = D-fructose [RN:R10817]
Reaction(KEGG)
Substrate
D-tagatose [CPD:C00795];
D-psicose [CPD:C06468]
Product
D-sorbose [CPD:C00764];
D-fructose [CPD:C00095]
Comment
The enzymes isolated from the bacteria Pseudomonas cichorii [2], Pseudomonas sp. ST-24 [1], Rhodobacter sphaeroides [3] and Mesorhizobium loti [4] catalyse the epimerization of various ketoses at the C-3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose. The specificity depends on the species. The enzymes from Pseudomonas cichorii and Rhodobacter sphaeroides require Mn2+ [2,3].
History
EC 5.1.3.31 created 2014
Orthology
K18910  
D-psicose/D-tagatose/L-ribulose 3-epimerase
Genes
SFO: 
VNI: 
MMT: 
BCEN: 
BMU: 
BMK: 
BGP: 
BGU: 
BGD: 
BGO: 
BYI: 
BUO: 
BUE: 
BPLA: 
BCAI: 
VEI: 
DAC: 
DEL: 
LIM: 
MLO: 
MCI: 
MOP: 
MAM: 
HOE: 
SME: 
SMK: 
SMQ: 
SMX: 
SMI: 
SMEG: 
SMEL: 
SMER: 
SMD: 
RHI: 
SFH: 
SFD: 
EAD: 
ATU: 
ARA: 
ATA: 
RET: 
REL: 
REI: 
RLE: 
RLT: 
RLG: 
RLB: 
RLU: 
RTR: 
RIR: 
RHL: 
RGA: 
NGL: 
NGG: 
SHZ: 
CHEL: 
DEQ: 
MEY: 
AUA: 
RSP: 
RSH: 
RSQ: 
RSK: 
RDE: 
RLI: 
DSH: 
MALG: 
PPHR: 
HAT: 
ABG: 
ABS: 
ABQ: 
CLS: 
CLB: 
CCE: 
ROB: 
BPRL: 
SCB: 
SBH: 
SDV: 
SALB: 
STRC: 
MIM: 
ARR: 
AAU: 
LMOI: 
IVA: 
MPH: 
NDA: 
NAL: 
NML: 
MMAR: 
SVI: 
KPHY: 
VMA: 
SNA: 
SYZ: 
SYY: 
SYNGTS_1069(sll1304)
SYT: 
SYNGTI_1069(sll1304)
SYS: 
SYNPCCN_1068(sll1304)
SYQ: 
SYNPCCP_1068(sll1304)
SYJ: 
SYNE: 
SYNP: 
GEN: 
CAP: 
MSV: 
CAA: 
SBU: 
SGP: 
STR: 
RBA: 
PSL: 
PLM: 
PBS: 
IPA: 
SACI: 
HHY: 
SHT: 
CMR: 
CAMU: 
DFE: 
SLI: 
SRD: 
RSI: 
EOL: 
FAE: 
FBT: 
FJO: 
FBC: 
ZGA: 
CIH: 
HJE: 
 » show all
Taxonomy
Reference
1
  Authors
Itoh, H., Okaya, H., Khan, A. R., Tajima, S., Hayakawa, S., Izumori, K.
  Title
Purification and characterization of D-tagatose 3-epimerase from Pseudomonas sp. ST-24.
  Journal
Biosci. Biotechnol. Biochem. 58 (1994) 2168-2171.
Reference
2  [PMID:17936787]
  Authors
Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S
  Title
Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.
  Journal
J. Mol. Biol. 374 (2007) 443-53.
Reference
3  [PMID:19205890]
  Authors
Zhang L, Mu W, Jiang B, Zhang T
  Title
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.
  Journal
Biotechnol. Lett. 31 (2009) 857-62.
  Sequence
Reference
4  [PMID:23470755]
  Authors
Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K
  Title
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.
  Journal
Biosci. Biotechnol. Biochem. 77 (2013) 511-5.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system