KEGG   ENZYME: 5.3.1.29Help
Entry
EC 5.3.1.29                 Enzyme                                 

Name
ribose 1,5-bisphosphate isomerase;
R15P isomerase;
ribulose 1,5-bisphosphate synthase;
RuBP synthase
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds
BRITE hierarchy
Sysname
alpha-D-ribose 1,5-bisphosphate aldose-ketose-isomerase
Reaction(IUBMB)
alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate [RN:R10555]
Reaction(KEGG)
Substrate
alpha-D-ribose 1,5-bisphosphate [CPD:C01151]
Product
D-ribulose 1,5-bisphosphate [CPD:C01182]
Comment
This archaeal enzyme is involved in AMP metabolism and CO2 fixation through type III RubisCO enzymes. The enzyme is activated by cAMP [2].
History
EC 5.3.1.29 created 2013
Orthology
K18237  
ribose 1,5-bisphosphate isomerase
Genes
ERB: 
BPW: 
WESB_1267(gcn3)
SRB: 
MJA: 
MFE: 
MVU: 
MFS: 
MJH: 
MIG: 
MAE: 
MOK: 
MAC: 
MA_0379(eif2B2)
MBA: 
MBY: 
MBW: 
MBAR: 
MBAK: 
MMA: 
MMJ: 
MVC: 
MEK: 
MLS: 
METM: 
MEF: 
MEQ: 
MSJ: 
MSZ: 
MSW: 
MTHE: 
MTHR: 
MHOR: 
MBU: 
MMET: 
MMH: 
MEV: 
MZH: 
MPY: 
MHZ: 
MTP: 
MCJ: 
MHI: 
MHU: 
MLA: 
MEM: 
MBG: 
MEMA: 
MPI: 
MBN: 
MFO: 
MPL: 
MPD: 
RCI: 
RRC408(eif2b2)
AFU: 
AFG: 
APO: 
AVE: 
AST: 
FPL: 
GAC: 
GAH: 
HAL: 
VNG_1853G(eif2ba)
HSL: 
HDL: 
HHB: 
NPH: 
HTI: 
HMU: 
HSU: 
HSF: 
HLA: 
HVO: 
HME: 
HGI: 
HBO: 
HTU: 
NMG: 
HXA: 
NAT: 
NPE: 
NGE: 
NOU: 
HALH: 
TAR: 
MAX: 
MER: 
MEAR: 
MARC: 
PHO: 
PH0208(PH0208)
PAB: 
PFU: 
PFI: 
PYN: 
PYA: 
PYS: 
PYC: 
TKO: 
TON: 
TGA: 
TSI: 
TBA: 
THE: 
THA: 
THM: 
TLT: 
THS: 
TNU: 
TEU: 
TGY: 
THV: 
TCH: 
PPAC: 
ABI: 
ACF: 
SMR: 
SHC: 
DKA: 
DMU: 
DFD: 
TAG: 
THG: 
HBU: 
PDL: 
TPE: 
THB: 
TCB: 
THF: 
LOKI: 
BARC: 
HAH: 
 » show all
Taxonomy
Reference
1  [PMID:17303759]
  Authors
Sato T, Atomi H, Imanaka T
  Title
Archaeal type III RuBisCOs function in a pathway for AMP metabolism.
  Journal
Science. 315 (2007) 1003-6.
  Sequence
[tko:TK0185]
Reference
2  [PMID:23065974]
  Authors
Aono R, Sato T, Yano A, Yoshida S, Nishitani Y, Miki K, Imanaka T, Atomi H
  Title
Enzymatic characterization of AMP phosphorylase and ribose-1,5-bisphosphate isomerase functioning in an archaeal AMP metabolic pathway.
  Journal
J. Bacteriol. 194 (2012) 6847-55.
  Sequence
[tko:TK0185]
Reference
3  [PMID:22511789]
  Authors
Nakamura A, Fujihashi M, Aono R, Sato T, Nishiba Y, Yoshida S, Yano A, Atomi H, Imanaka T, Miki K
  Title
Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1.
  Journal
J. Biol. Chem. 287 (2012) 20784-96.
  Sequence
[tko:TK0185]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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