KEGG   ENZYME: 5.3.2.4Help
Entry
EC 5.3.2.4                  Enzyme                                 

Name
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming);
TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase (ambiguous);
Tyl1a;
dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase (ambiguous)
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
BRITE hierarchy
Sysname
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose isomerase
Reaction(IUBMB)
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose [RN:R06424]
Reaction(KEGG)
Substrate
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose [CPD:C11907]
Product
dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose [CPD:C11908]
Comment
The enzyme is involved in biosynthesis of D-mycaminose.
History
EC 5.3.2.4 created 2011
Pathway
Polyketide sugar unit biosynthesis
Biosynthesis of antibiotics
Orthology
K19853  
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase
Genes
SAMB: 
Taxonomy
Reference
1  [PMID:17209568]
  Authors
Melancon CE 3rd, Hong L, White JA, Liu YN, Liu HW
  Title
Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and  substrate specificity studies.
  Journal
Biochemistry. 46 (2007) 577-90.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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