KEGG   ENZYME: 5.3.2.7Help
Entry
EC 5.3.2.7                  Enzyme                                 

Name
ascopyrone tautomerase;
ascopyrone isomerase;
ascopyrone intramolecular oxidoreductase;
1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase;
APM tautomerase;
ascopyrone P tautomerase;
APTM
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
BRITE hierarchy
Sysname
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose Delta3-Delta1-isomerase
Reaction(IUBMB)
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose [RN:R09705]
Reaction(KEGG)
Substrate
1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose [CPD:C19822]
Product
1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose [CPD:C19826]
Comment
This enzyme catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose [1,2]. The other enzymes involved in this pathway are EC 4.2.1.110 (aldos-2-ulose dehydratase), EC 4.2.1.111 (1,5-anhydro-D-fructose dehydratase) and EC 4.2.2.13 [exo-(1->4)-alpha-D-glucan lyase]. Ascopyrone P is an anti-oxidant [2].
History
EC 5.3.2.7 created 2006 as EC 5.3.3.15, transferred 2012 to EC 5.3.2.7
Reference
1  [PMID:15110094]
  Authors
Yu S, Refdahl C, Lundt I.
  Title
Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma.
  Journal
Biochim. Biophys. Acta. 1672 (2004) 120-9.
Reference
2  [PMID:16822618]
  Authors
Yu S, Fiskesund R.
  Title
The anhydrofructose pathway and its possible role in stress response and signaling.
  Journal
Biochim. Biophys. Acta. 1760 (2006) 1314-22.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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