KEGG   ENZYME: 5.4.2.9Help
Entry
EC 5.4.2.9                  Enzyme                                 

Name
phosphoenolpyruvate mutase;
phosphoenolpyruvate-phosphonopyruvate phosphomutase;
PEP phosphomutase;
phosphoenolpyruvate phosphomutase;
PEPPM;
PEP phosphomutase
Class
Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)
BRITE hierarchy
Sysname
phosphoenolpyruvate 2,3-phosphonomutase
Reaction(IUBMB)
phosphoenolpyruvate = 3-phosphonopyruvate [RN:R00661]
Reaction(KEGG)
Substrate
phosphoenolpyruvate [CPD:C00074]
Product
3-phosphonopyruvate [CPD:C02798]
Comment
Involved in the biosynthesis of the C-P bond, although the equilibrium greatly favours phosphoenolpyruvate.
History
EC 5.4.2.9 created 1990
Pathway
Phosphonate and phosphinate metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Microbial metabolism in diverse environments
Orthology
K01841  
phosphoenolpyruvate phosphomutase
Genes
PHD: 
NVE: 
HMG: 
ACAN: 
TET: 
PTM: 
TCR: 
ECA: 
ECA0487(fom1)
PCT: 
PCC: 
PWA: 
PEC: 
PLU: 
SOD: 
Sant_3984(pepM)
SRL: 
SRY: 
EIC: 
HDE: 
PAM: 
PANA_3291(pepM)
PLF: 
PAJ: 
PAQ: 
VFI: 
PSYR: 
PFL: 
PFL_2141(aepX)
PPRC: 
PFC: 
PPZ: 
PEN: 
SDN: 
NOC: 
NHL: 
NWA: 
RPJ: 
RME: 
Rmet_1808(pepM)
BMA: 
BMAA1768(pepM)
BMV: 
BML: 
BMN: 
BPS: 
BPM: 
BPL: 
BPD: 
BPSE: 
BDL_3735(aepX) BDL_3837(aepX)
BPSM: 
BBQ_5585(aepX) BBQ_5687(aepX)
BPSU: 
BBN_3909(aepX) BBN_4009(aepX)
BPSD: 
BBX_5572(aepX) BBX_5674(aepX)
BPZ: 
BPQ: 
BPK: 
BBK_3881(aepX) BBK_5714(aepX)
BTE: 
BTQ: 
BTQ_5190(aepX)
BTJ: 
BTJ_3820(aepX)
BTZ: 
BTL_4576(aepX) BTL_4676(aepX)
BTD: 
BVI: 
BUR: 
BCN: 
BCH: 
BCM: 
BCJ: 
BAM: 
BAC: 
BMU: 
BMJ: 
BCT: 
BXE: 
BPH: 
BPY: 
BGL: 
BUG: 
BGE: 
BGF: 
BRH: 
BGD: 
BYI: 
BUK: 
BPX: 
BUO: 
PPK: 
PPNO: 
PRB: 
BPAR: 
BBR: 
BB1046(pepM)
BBM: 
BBH: 
BHO: 
AXY: 
AXO: 
AXN: 
AAV: 
AAA: 
VPD: 
AZO: 
azo2698(pepM)
HCP: 
HCB: 
CJU: 
ANT: 
NSA: 
PCA: 
PPD: 
DAK: 
DAL: 
SCL: 
sce7305(pepM)
SCU: 
DAO: 
MLO: 
SMK: 
ARA: 
AVI: 
RTR: 
AOL: 
RPC: 
TMO: 
BSS: 
BSUB: 
BYA: 
BAMB: 
BQY: 
BMQ: 
BMQ_0784(aepX)
BMD: 
BMD_0785(aepX)
BMH: 
BACI: 
PPY: 
PPOL: 
PTA: 
PLV: 
SNX: 
SPNE: 
SPNU: 
SPNM: 
SPNO: 
CTC: 
CTET: 
CBJ: 
CBE: 
CSR: 
CSB: 
RAL: 
RCH: 
CLE: 
RIX: 
HAS: 
SSG: 
NBR: 
SDV: 
SCI: 
KSK: 
FRA: 
FAL: 
KAL: 
SAQ: 
SNA: 
AYM: 
OLS: 
TDE: 
TBE: 
TAZ: 
TPI: 
SCD: 
SSM: 
STA: 
SBU: 
SGP: 
TPX: 
BIP: 
FSU: 
FSC: 
ARP: 
BTH: 
BFR: 
BFS: 
BF1897(aepX)
BFG: 
NDE: 
TAR: 
NMR: 
 » show all
Taxonomy
Reference
1
  Authors
Bowman, E., McQueney, M., Barry, R.J. and Dunaway-Mariano, D.
  Title
Catalysis and thermodynamics of the phosphoenolpyruvate phosphonopyruvate rearrangement - entry into the phosphonate class of naturally-occurring organo-phosphorus compounds.
  Journal
J. Am. Chem. Soc. 110 (1988) 5575-5576.
Reference
2  [PMID:2160937]
  Authors
Hidaka T, Imai S, Hara O, Anzai H, Murakami T, Nagaoka K, Seto H.
  Title
Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.
  Journal
J. Bacteriol. 172 (1990) 3066-72.
  Organism
Streptomyces hygroscopicus
Reference
3  [PMID:3138545]
  Authors
Seidel HM, Freeman S, Seto H, Knowles JR.
  Title
Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond.
  Journal
Nature. 335 (1988) 457-8.
  Organism
Tetrahymena pyriformis
  Sequence
[up:P33182]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
115756-49-5

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