KEGG   ENZYME: 5.4.3.7Help
Entry
EC 5.4.3.7                  Enzyme                                 

Name
leucine 2,3-aminomutase
Class
Isomerases;
Intramolecular transferases;
Transferring amino groups
BRITE hierarchy
Sysname
(2S)-alpha-leucine 2,3-aminomutase
Reaction(IUBMB)
(2S)-alpha-leucine = (3R)-beta-leucine [RN:R01091]
Reaction(KEGG)
Substrate
(2S)-alpha-leucine [CPD:C00123]
Product
(3R)-beta-leucine [CPD:C02486]
Comment
Requires a cobamide coenzyme.
History
EC 5.4.3.7 created 1982
Reference
1
  Authors
Freer, I., Pedrocchi-Fantoni, G., Picken, D.J. and Overton, K.H.
  Title
Stereochemistry of the leucine 2,3-aminomutase from tissue-cultures of Andrographis paniculata.
  Journal
J. Chem. Soc. Chem. Commun. (1981) 80-82.
Reference
2  [PMID:1270414]
  Authors
Poston JM.
  Title
Leucine 2,3-aminomutase, an enzyme of leucine catabolism.
  Journal
J. Biol. Chem. 251 (1976) 1859-63.
Reference
3
  Authors
Poston, J.M.
  Title
Coenzyme B12-dependent enzymes in potatoes: leucine 2,3-aminomutase and methylmalonyl-CoA mutase.
  Journal
Phytochemistry 17 (1976) 401-402.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
59125-53-0

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