KEGG   ENZYME: 5.4.3.9Help
Entry
EC 5.4.3.9                  Enzyme                                 

Name
glutamate 2,3-aminomutase
Class
Isomerases;
Intramolecular transferases;
Transferring amino groups
BRITE hierarchy
Sysname
L-glutamate 2,3-aminomutase
Reaction(IUBMB)
L-glutamate = 3-aminopentanedioate [RN:R10153]
Reaction(KEGG)
Substrate
L-glutamate [CPD:C00025]
Product
3-aminopentanedioate [CPD:C05574]
Comment
This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.
History
EC 5.4.3.9 created 2012
Orthology
K19814  
glutamate 2,3-aminomutase
Genes
CCB: 
CACE: 
AMT: 
CSS: 
Cst_c09560(kamA1)
CSD: 
CSH: 
CAD: 
CDF: 
PDC: 
CDC: 
CDL: 
CDG: 
PDF: 
SWO: 
SLP: 
DSY: 
DHD: 
DDH: 
DDL: 
DMT: 
DRM: 
DAE: 
DCA: 
DKU: 
DRU: 
DGI: 
PTH: 
PTH_0616(KamA)
DAU: 
TJR: 
SGY: 
DOR: 
DAI: 
DMI: 
DED: 
DEC: 
DRS: 
TTE: 
TTE1204(KamA2)
CHY: 
MTA: 
ADG: 
TPZ: 
CSC: 
ATE: 
COB: 
CHD: 
COW: 
CKI: 
CKN: 
CLC: 
NTH: 
MMIL: 
MEYE: 
 » show all
Taxonomy
Reference
1  [PMID:17222594]
  Authors
Ruzicka FJ, Frey PA
  Title
Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.
  Journal
Biochim. Biophys. Acta. 1774 (2007) 286-96.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system