KEGG   ENZYME: 5.4.99.33Help
Entry
EC 5.4.99.33                Enzyme                                 

Name
cucurbitadienol synthase;
CPQ (gene name);
(S)-2,3-epoxysqualene mutase (cyclizing, cucurbitadienol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cucurbitadienol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = cucurbitadienol [RN:R09688]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
cucurbitadienol [CPD:C19819]
History
EC 5.4.99.33 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K15812  
cucurbitadienol synthase
Genes
CSV: 
CMO: 
Taxonomy
Reference
1
  Authors
Shibuya, M., Adachi, S., and Ebizuka, Y.
  Title
Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis.
  Journal
Tetrahedron 60 (2004) 6995-7003.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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