KEGG   ENZYME: 5.4.99.34Help
Entry
EC 5.4.99.34                Enzyme                                 

Name
germanicol synthase;
RsM1;
(S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualenee mutase (cyclizing, germanicol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = germanicol [RN:R09710]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
germanicol [CPD:C19833]
Comment
The enzyme produces germanicol, beta-amyrin and lupeol in the ratio 63:33:4.
History
EC 5.4.99.34 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15818  
germanicol synthase
Reference
1  [PMID:17803686]
  Authors
Basyuni M, Oku H, Tsujimoto E, Kinjo K, Baba S, Takara K
  Title
Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae.
  Journal
FEBS. J. 274 (2007) 5028-42.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system