KEGG   ENZYME: 5.4.99.38Help
Entry
EC 5.4.99.38                Enzyme                                 

Name
camelliol C synthase;
CAMS1;
LUP3 (gene name)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C [RN:R09713]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
camelliol C [CPD:C19835]
Comment
The product is 97% camelliol, 2% achilleol A and 0.2% beta-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC 5.4.99.39, beta-amyrin synthase.
History
EC 5.4.99.38 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15822  
camelliol C synthase
Genes
ATH: 
AT1G78955(CAMS1)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
Taxonomy
Reference
1  [PMID:17985917]
  Authors
Kolesnikova MD, Wilson WK, Lynch DA, Obermeyer AC, Matsuda SP
  Title
Arabidopsis camelliol C synthase evolved from enzymes that make pentacycles.
  Journal
Org. Lett. 9 (2007) 5223-6.
  Sequence
[ath:AT1G78955]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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