KEGG   ENZYME: 5.5.1.18Help
Entry
EC 5.5.1.18                 Enzyme                                 

Name
lycopene epsilon-cyclase;
CrtL-e;
LCYe;
carotenoid psi-end group lyase (decyclizing)
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
carotenoid psi-end group lyase (ring-opening)
Reaction(IUBMB)
carotenoid psi-end group = carotenoid epsilon-end group
Reaction(KEGG)
Substrate
carotenoid psi-end group
Product
carotenoid epsilon-end group
Comment
The carotenoid lycopene has the psi-end group at both ends. When acting on one end, this enzyme forms delta-carotene. When acting on both ends, it forms epsilon-carotene.
History
EC 5.5.1.18 created 2011
Pathway
Carotenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K06444  
lycopene epsilon-cyclase
Genes
ATH: 
AT5G57030(LUT2)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
102578059(CSLECY)
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj6g3v1211980.1(Lj6g3v1211980.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
103498607(LCYE)
RCU: 
JCU: 
POP: 
VVI: 
100259482(LECY1)
SLY: 
544129(CrtL-e-1)
SPEN: 
SOT: 
102577922(LCYe)
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0581300-01(Os01g0581300)
OBR: 
BDI: 
SBI: 
SORBI_03g026020(SORBIDRAFT_03g026020)
ZMA: 
100280448(lyce1)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
OLU: 
CSL: 
CVR: 
APRO: 
PMA: 
Pro_0790(lcyE)
PMM: 
PMM0633(crtL2)
PMT: 
PMN: 
PMI: 
PMB: 
PMC: 
PMF: 
PMG: 
PMH: 
PMJ: 
PME: 
PRC: 
PRM: 
 » show all
Taxonomy
Reference
1  [PMID:11226339]
  Authors
Cunningham FX Jr, Gantt E.
  Title
One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 2905-10.
  Sequence
[ath:AT5G57030]
Reference
2  [PMID:12712234]
  Authors
Stickforth P, Steiger S, Hess WR, Sandmann G.
  Title
A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4.
  Journal
Arch. Microbiol. 179 (2003) 409-15.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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