KEGG   ENZYME: 6.2.1.9Help
Entry
EC 6.2.1.9                  Enzyme                                 

Name
malate---CoA ligase;
malyl-CoA synthetase;
malyl coenzyme A synthetase;
malate thiokinase
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
BRITE hierarchy
Sysname
malate:CoA ligase (ADP-forming)
Reaction(IUBMB)
ATP + malate + CoA = ADP + phosphate + malyl-CoA [RN:R01256]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
malate [CPD:C00149];
CoA [CPD:C00010]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
malyl-CoA [CPD:C04348]
History
EC 6.2.1.9 created 1972
Pathway
Glyoxylate and dicarboxylate metabolism
Methane metabolism
Microbial metabolism in diverse environments
Orthology
K08692  
malate-CoA ligase subunit alpha
K14067  
malate-CoA ligase subunit beta
Genes
MCA: 
MCA1740(sucC-2) MCA1741(sucD-2)
MMT: 
MAH: 
BPH: 
MPT: 
NEU: 
NET: 
NIT: 
NII: 
NMU: 
MLO: 
MOP: 
MAM: 
RHI: 
SFH: 
SFD: 
MEX: 
MEA: 
MDI: 
METDI2482(mtkA) METDI2483(mtkB)
MCH: 
MRD: 
MET: 
MPO: 
MNO: 
MSL: 
HDN: 
HDT: 
HMC: 
HNI: 
MSC: 
SIL: 
RDE: 
RD1_1162(sucC) RD1_4246(mtkB)
RLI: 
PAMI: 
DSH: 
Dshi_2491(sucC2) Dshi_2492(sucD2)
LMD: 
RED: 
GBE: 
GBH: 
 » show all
Taxonomy
Reference
1  [PMID:14244056]
  Authors
MUE S, TUBOI S, KIKUCHI G.
  Title
ON MALYL-COENZYME A SYNTHETASE.
  Journal
J. Biochem. 56 (1964) 545-51.
  Organism
Rhodopseudomonas spheroides
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37318-58-4

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