KEGG   ENZYME: 6.3.1.17Help
Entry
EC 6.3.1.17                 Enzyme                                 

Name
beta-citrylglutamate synthase;
NAAG synthetase I;
NAAGS-I;
RIMKLB (gene name) (ambiguous)
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
BRITE hierarchy
Sysname
citrate:L-glutamate ligase (ADP-forming)
Reaction(IUBMB)
ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate [RN:R10677]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
citrate [CPD:C00158];
L-glutamate [CPD:C00025]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
beta-citryl-L-glutamate [CPD:C20775]
Comment
The enzyme, found in animals, also has the activity of EC 6.3.2.41, N-acetylaspartylglutamate synthase.
History
EC 6.3.1.17 created 2014
Pathway
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Orthology
K18310  
beta-citrylglutamate/N-acetylaspartylglutamate synthase
Genes
HSA: 
57494(RIMKLB)
PTR: 
735860(RIMKLB)
PPS: 
100974820(RIMKLB)
GGO: 
101136567(RIMKLB)
PON: 
100441104(RIMKLB)
NLE: 
100593570(RIMKLB)
MCC: 
722261(RIMKLB)
MCF: 
102124154(RIMKLB)
CSAB: 
103218536(RIMKLB)
RRO: 
104672842(RIMKLB)
CJC: 
100406491(RIMKLB)
SBQ: 
101033047(RIMKLB)
MMU: 
108653(Rimklb)
RNO: 
362428(Rimklb)
CGE: 
100760031(Rimklb)
NGI: 
103727467(Rimklb)
HGL: 
101706744(Rimklb)
OCU: 
100346793(RIMKLB)
TUP: 
102472940(RIMKLB)
CFA: 
486698(RIMKLB)
AML: 
100473320(RIMKLB)
UMR: 
103669163(RIMKLB)
FCA: 
101097740(RIMKLB)
PTG: 
102963865(RIMKLB)
BTA: 
538579(RIMKLB)
BOM: 
102269649(RIMKLB)
PHD: 
102321435(RIMKLB)
CHX: 
102176861(RIMKLB)
OAS: 
101102554(RIMKLB)
SSC: 
100152915(RIMKLB)
CFR: 
102503881(RIMKLB)
BACU: 
103019013(RIMKLB)
LVE: 
103069710(RIMKLB)
ECB: 
100061350(RIMKLB)
MYB: 
102245342(RIMKLB)
MYD: 
102752373(RIMKLB)
PALE: 
102880426(RIMKLB)
LAV: 
100657534(RIMKLB)
MDO: 
100013787(RIMKLB)
SHR: 
100930894(RIMKLB)
OAA: 
GGA: 
418255(RIMKLB)
MGP: 
CJO: 
107318392(RIMKLB)
APLA: 
101792875(RIMKLB)
TGU: 
100220208(RIMKLB)
GFR: 
102035986(RIMKLB)
FAB: 
101814507(RIMKLB)
PHI: 
102111957(RIMKLB)
CCW: 
104690266(RIMKLB)
FPG: 
101913481(RIMKLB)
FCH: 
102056126(RIMKLB)
CLV: 
102098362(RIMKLB)
AAM: 
106495722(RIMKLB)
ASN: 
102373845(RIMKLB)
AMJ: 
102576775(RIMKLB)
PSS: 
102451018(RIMKLB)
CMY: 
102933090(RIMKLB)
ACS: 
100563778(rimklb)
PBI: 
103055545(RIMKLB)
GJA: 
107117747(RIMKLB)
XTR: 
100486701(rimklb)
DRE: 
447815(rimkla)
TRU: 
TNG: 
MZE: 
OLA: 
101169452(rimkla)
XMA: 
SASA: 
LCM: 
102351441(RIMKLB) 102354509(RIMKLA)
CMK: 
103190080(rimkla)
SALU: 
SALL: 
STRE: 
SLD: 
SRW: 
 » show all
Taxonomy
Reference
1  [PMID:20657015]
  Authors
Collard F, Stroobant V, Lamosa P, Kapanda CN, Lambert DM, Muccioli GG, Poupaert JH, Opperdoes F, Van Schaftingen E
  Title
Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
  Journal
J. Biol. Chem. 285 (2010) 29826-33.
  Sequence
[mmu:108653]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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