KEGG   ENZYME: 6.3.1.6Help
Entry
EC 6.3.1.6                  Enzyme                                 

Name
glutamate---ethylamine ligase;
N5-ethyl-L-glutamine synthetase;
theanine synthetase;
N5-ethylglutamine synthetase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
BRITE hierarchy
Sysname
L-glutamate:ethylamine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + ethylamine = ADP + phosphate + N5-ethyl-L-glutamine [RN:R02929]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
ethylamine [CPD:C00797]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-ethyl-L-glutamine [CPD:C01047]
History
EC 6.3.1.6 created 1976
Reference
1
  Authors
Sasaoka, K. and Kito, M.
  Title
Synthesis of theanine by tea seedling homogenate.
  Journal
Agric. Biol. Chem. 28 (1964) 313-317.
Reference
2
  Authors
Sasaoka, K., Kito, M. and Inagaki, H.
  Title
Studies on the biosynthesis of theanine in tea seedlings. Synthesis of theanine by the homogenate of tea seedlings.
  Journal
Agric. Biol. Chem. 27 (1963) 467-468.
Reference
3
  Authors
Sasaoka, K., Kito, M. and Onishi, Y.
  Title
Some properties of the theanine synthesizing enzyme in tea seedlings.
  Journal
Agric. Biol. Chem. 29 (1965) 984-988.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62213-31-4

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