KEGG   ENZYME: 6.3.2.16Help
Entry
EC 6.3.2.16                 Enzyme                                 

Name
D-alanine---alanyl-poly(glycerolphosphate) ligase;
D-alanyl-alanyl-poly(glycerolphosphate) synthetase;
D-alanine:membrane-acceptor ligase;
D-alanylalanylpoly(phosphoglycerol) synthetase;
D-alanyl-poly(phosphoglycerol) synthetase;
D-alanine-membrane acceptor-ligase
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)
BRITE hierarchy
Sysname
D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)
Reaction(IUBMB)
ATP + D-alanine + alanyl-poly(glycerolphosphate) = ADP + phosphate + D-alanyl-alanyl-poly(glycerolphosphate) [RN:R04369]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
D-alanine [CPD:C00133];
alanyl-poly(glycerolphosphate) [CPD:C03999]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
D-alanyl-alanyl-poly(glycerolphosphate) [CPD:C04457]
Comment
Involved in the synthesis of teichoic acids.
History
EC 6.3.2.16 created 1976
Pathway
D-Alanine metabolism
Reference
1  [PMID:4399593]
  Authors
Reusch VM Jr, Neuhaus FC.
  Title
D-Alanine: membrane acceptor ligase from Lactobacillus casei.
  Journal
J. Biol. Chem. 246 (1971) 6136-43.
  Organism
Lactobacillus casei
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9046-58-6

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