KEGG   ENZYME: 6.3.4.1Help
Entry
EC 6.3.4.1                  Enzyme                                 
Name
GMP synthase;
xanthosine-5'-phosphate---ammonia ligase;
guanylate synthetase;
XMP aminase;
xanthosine 5'-monophosphate aminase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
BRITE hierarchy
Sysname
xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
Reaction(IUBMB)
ATP + XMP + NH3 = AMP + diphosphate + GMP [RN:R01230]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
XMP [CPD:C00655];
NH3 [CPD:C00014]
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
GMP [CPD:C00144]
Pathway
Purine metabolism
Metabolic pathways
Reference
1  [PMID:13428768]
  Authors
MOYED HS, MAGASANIK B.
  Title
Enzymes essential for the biosynthesis of nucleic acid guanine; xanthosine 5'-phosphate aminase of Aerobacter aerogenes.
  Journal
J. Biol. Chem. 226 (1957) 351-63.
  Organism
Aerobacter aerogenes
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9023-55-6
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