KEGG   ENZYME: 6.3.4.12Help
Entry
EC 6.3.4.12                 Enzyme                                 

Name
glutamate---methylamine ligase;
gamma-glutamylmethylamide synthetase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
BRITE hierarchy
Sysname
L-glutamate:methylamine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine [RN:R01585]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
methylamine [CPD:C00218]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-methyl-L-glutamine [CPD:C03153]
History
EC 6.3.4.12 created 1972
Reference
1  [PMID:5800436]
  Authors
Kung HF, Wagner C.
  Title
Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine.
  Journal
J. Biol. Chem. 244 (1969) 4136-40.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37318-69-7

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