| Entry |
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| Name |
biotin---[methylmalonyl-CoA-carboxytransferase] ligase;
biotin-[methylmalonyl-CoA-carboxyltransferase] synthetase;
biotin-methylmalonyl coenzyme A carboxyltransferase synthetase;
biotin-transcarboxylase synthetase;
methylmalonyl coenzyme A holotranscarboxylase synthetase;
biotin---[methylmalonyl-CoA-carboxyltransferase] ligase;
biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming)
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| Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
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| Sysname |
biotin:apo[methylmalonyl-CoA:pyruvate carboxytransferase] ligase (AMP-forming)
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| Reaction(IUBMB) |
ATP + biotin + apo-[methylmalonyl-CoA:pyruvate carboxytransferase] = AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxytransferase] [RN: R04563]
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| Reaction(KEGG) |
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| Substrate |
ATP [CPD: C00002];
biotin [CPD: C00120];
apo-[methylmalonyl-CoA:pyruvate carboxytransferase] [CPD: C04736]
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| Product |
AMP [CPD: C00020];
diphosphate [CPD: C00013];
[methylmalonyl-CoA:pyruvate carboxytransferase] [CPD: C04682]
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| Pathway |
| Biotin metabolism | | Metabolic pathways |
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| Orthology |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XTR: | | DRE: | | TRU: | | OLA: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | TCA: | | API: | | PHU: | | ISC: | | BMY: | | SMM: | | NVE: | | TAD: | | AQU: | | CRE: | | SCE: | | AGO: | | ERC: | | KLA: | | LTH: | | PPA: | | VPO: | | ZRO: | | CGR: | | NCS: | | NDI: | | TPF: | | TBL: | | TDL: | | KAF: | | DHA: | | PIC: | | PGU: | | LEL: | | CAL: | | CTP: | | CDU: | | COT: | | YLI: | | CLU: | | NCR: | | SMP: | | PAN: | | TTT: | | MTM: | | MGR: | | FGR: | | NHE: | | VAL: | | SSL: | | BFU: | | ANI: | | NFI: | | AFM: | | AOR: | | AFV: | | ACT: | | CIM: | | CPW: | | PBL: | | URE: | | ABE: | | TVE: | | AJE: | | PNO: | | PTE: | | ZTR: | | TML: | | SPO: | | CNE: | | CNB: | | CGI: | | LBC: | | CCI: | | SCM: | | UMA: | | MGL: | | PGR: | | DPP: | |
» show all
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| Reference |
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| Authors |
LANE MD, YOUNG DL, LYNEN F. |
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| Title |
THE ENZYMATIC SYNTHESIS OF HOLOTRANSCARBOXYLASE FROM APOTRANSCARBOXYLASE AND (+)-BIOTIN. I. PURIFICATION OF THE APOENZYME AND SYNTHETASE; CHARACTERISTICS OF THE REACTION. |
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| Journal |
J. Biol. Chem. 239 (1964) 2858-64. |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 37318-66-4 |
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