KEGG   ENZYME: 6.4.1.5Help
Entry
EC 6.4.1.5                  Enzyme                                 

Name
geranoyl-CoA carboxylase;
geranoyl coenzyme A carboxylase;
geranyl-CoA carboxylase
Class
Ligases;
Forming carbon-carbon bonds;
Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
BRITE hierarchy
Sysname
geranoyl-CoA:carbon-dioxide ligase (ADP-forming)
Reaction(IUBMB)
ATP + geranoyl-CoA + HCO3- = ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA [RN:R03494]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
geranoyl-CoA [CPD:C01920];
HCO3- [CPD:C00288]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA [CPD:C01291]
Comment
A biotinyl-protein. Also carboxylates dimethylpropenoyl-CoA and farnesoyl-CoA.
History
EC 6.4.1.5 created 1972
Pathway
Geraniol degradation
Biosynthesis of secondary metabolites
Orthology
K13777  
geranyl-CoA carboxylase alpha subunit
K13778  
geranyl-CoA carboxylase beta subunit
Genes
DJI: 
PAE: 
PA2888(atuC) PA2891(atuF)
PAU: 
PAP: 
PAG: 
PAF: 
PNC: 
PDK: 
PSG: 
PRP: 
PAEP: 
PAER: 
PAEM: 
PAEL: 
PAES: 
PAEU: 
PAEG: 
PPUU: 
PFL: 
PFL_4196(atuC) PFL_4199(atuF)
PPRC: 
PFO: 
PFS: 
PFE: 
PFC: 
PMY: 
PMK: 
PBA: 
PDR: 
PRE: 
PSK: 
PKC: 
PKB_3703(l(2)04524) PKB_3706(MCCC1)
ACD: 
ACB: 
ABM: 
ABY: 
ABC: 
ABN: 
ABB: 
ABX: 
ABZ: 
ABR: 
ABD: 
ABH: 
ABAD: 
ABJ: 
ABAB: 
ABAJ: 
ABAZ: 
ACC: 
PAT: 
MAQ: 
MHC: 
MAD: 
AMB: 
GAG: 
CYQ: 
CZA: 
HCH: 
ABO: 
ABO_0986(accA) ABO_0989(accD)
ADI: 
SAGA: 
GPB: 
RPI: 
RPF: 
REU: 
REH: 
H16_A2144(pccB)
CNC: 
RME: 
Rmet_1721(pccB) Rmet_1724(accC)
BPS: 
BPM: 
BPL: 
BPD: 
BPSE: 
BPSU: 
BPZ: 
BPQ: 
BPK: 
BTE: 
BTD: 
AXY: 
AKA: 
RFR: 
AAA: 
ACK: 
VEI: 
VAP: 
VPE: 
VPD: 
CTT: 
ADN: 
ADK: 
RGE: 
MXA: 
MXAN_0081(accB) MXAN_0082(accC)
MFU: 
MSD: 
CCX: 
BJA: 
blr0986(mccB) blr0987(mccA)
BJU: 
BRA: 
BBT: 
BRS: 
S23_68190(mccA) S23_68200(mccB)
AOL: 
RPA: 
RPB: 
RPC: 
RPD: 
RPE: 
RPT: 
RPX: 
RVA: 
SIL: 
PSF: 
RCE: 
TMO: 
 » show all
Taxonomy
Reference
1  [PMID:14087299]
  Authors
SEUBERT W, FASS E, REMBERGER U.
  Title
[STUDIES ON THE BACTERIAL DEGRADATION OF ISOPRENOID COMPOUNDS. III. PURIFICATION AND PROPERTIES OF GERANYL CARBOXYLASE.]
  Journal
Biochem. Z. 338 (1963) 265-75.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37324-35-9

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