KEGG   Equus caballus (horse): 100009710Help
Entry
100009710         CDS       T01058                                 

Gene name
PRKAA1
Definition
(RefSeq) protein kinase AMP-activated catalytic subunit alpha 1
  KO
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
ecb  Equus caballus (horse)
Pathway
FoxO signaling pathway
Autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Glucagon signaling pathway
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100009710 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    100009710 (PRKAA1)
   04152 AMPK signaling pathway
    100009710 (PRKAA1)
   04150 mTOR signaling pathway
    100009710 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy
    100009710 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100009710 (PRKAA1)
   04922 Glucagon signaling pathway
    100009710 (PRKAA1)
   04920 Adipocytokine signaling pathway
    100009710 (PRKAA1)
   04921 Oxytocin signaling pathway
    100009710 (PRKAA1)
  Aging
   04211 Longevity regulating pathway - mammal
    100009710 (PRKAA1)
   04213 Longevity regulating pathway - multiple species
    100009710 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    100009710 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100009710 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100009710 (PRKAA1)
   04931 Insulin resistance
    100009710 (PRKAA1)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100009710 (PRKAA1)
Protein kinases [BR:ecb01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100009710 (PRKAA1)
Mitochondrial biogenesis [BR:ecb03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100009710 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    100009710 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
21q16-q17prox
AA seq 559 aa AA seqDB search
MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE
ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEASLTSSVTSLDSSPVDLTPRPG
SHTIEFFEMCANLIKILAQ
NT seq 1680 nt NT seq  +upstreamnt  +downstreamnt
atgcgcagactcagttcctggagaaagatggcgacagccgagaagcagaaacacgacggg
cgggtgaagatcggccactacatcctgggggacacgctgggggtcggcacgttcggcaaa
gtgaaggttggcaaacatgaattgactgggcataaagttgctgtgaagatactcaatcgc
cagaagattcgaagcctcgatgtggttggaaaaatccgcagagaaattcagaacctcaag
cttttcaggcatcctcatataattaaactgtaccaggtcatcagtacaccatctgatatt
ttcatggtgatggaatatgtctcaggaggagagctatttgattatatctgtaaaaatgga
aggctcgatgaaaaagaaagtcgacgtctgttccaacagatcctttctggtgtggattat
tgtcacaggcatatggtggtccatagagacttgaaacctgaaaacgtcctgcttgatgca
cacatgaatgcaaagatagctgattttggtctttcaaacatgatgtcagatggtgaattt
ttaagaacgagttgtggctcacccaactatgctgccccagaggtcatttcaggaagattg
tatgcaggcccagaggtagacatatggagcagcggggttattctctatgctttattatgt
ggaacccttccatttgatgatgatcatgtgccaactctttttaagaagatatgtgatggg
atcttttatacccctcagtatttaaatccatccgtgattagccttttgaaacatatgctg
caggtggatcccatgaagcgggccacaatcaaagatatcagggaacatgaatggtttaaa
caagaccttccaaaatatctctttcctgaggacccatcatatagttcaactatgattgat
gatgaagccttaaaagaagtatgtgaaaaatttgaatgctcagaagaggaggttctcagc
tgcctttataaccgaaatcaccaggaccctttggcagtggcctaccacctcatcatagat
aacaggagaataatgaatgaagccaaagatttttacttggcgacaagcccacctgattct
tttcttgatgatcaccatttgactcggccccatcctgaaagagtaccattcttggttgct
gaaacaccaagggcacgccatactctcgatgaattaaatccacagaaatccaaacaccaa
ggtgtaagaaaagccaaatggcatttgggaattagaagtcaaagtcgaccaaatgatatc
atggcagaagtttgtagagcaattaaacaactggattatgaatggaaggttgtaaaccca
tattacttgcgtgttcgaaggaagaatcctgtgacaagtacctactccaaaatgagtcta
cagttataccaagtggacagtagaacatacttactggatttccgtagtattgatgatgaa
attactgaagccaaatccgggactgctactccacaaagatcgggatccgttagcaactat
cgatcttgtcagaggagtgattcggatgctgaggctcaaggaaaatcctcagaagcttct
cttacctcatcggtgacctcacttgactcttctcctgttgacttaactccaagacctgga
agtcacacaatagagttttttgagatgtgtgcgaatctaattaaaattcttgcacagtaa

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