KEGG   Equus caballus (horse): 100009710Help
Entry
100009710         CDS       T01058                                 

Gene name
PRKAA1
Definition
protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.1.-)
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
ecb  Equus caballus (horse)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100009710 (PRKAA1)
   04151 PI3K-Akt signaling pathway
    100009710 (PRKAA1)
   04152 AMPK signaling pathway
    100009710 (PRKAA1)
   04150 mTOR signaling pathway
    100009710 (PRKAA1)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100009710 (PRKAA1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100009710 (PRKAA1)
   04920 Adipocytokine signaling pathway
    100009710 (PRKAA1)
   04921 Oxytocin signaling pathway
    100009710 (PRKAA1)
  Environmental adaptation
   04710 Circadian rhythm
    100009710 (PRKAA1)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100009710 (PRKAA1)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100009710 (PRKAA1)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100009710 (PRKAA1)
Protein kinases [BR:ecb01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100009710 (PRKAA1)
Mitochondrial biogenesis [BR:ecb03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100009710 (PRKAA1)
  Mitophagy factors
   Other mitophagy factors
    100009710 (PRKAA1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
21q16-q17prox
AA seq 550 aa AA seqDB search
MATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVV
GKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRR
LFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPN
YAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLN
PSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCE
KFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTR
PHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIK
QLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTA
TPQRSGSVSNYRSCQRSDSDAEAQGKSSEASLTSSVTSLDSSPVDLTPRPGSHTIEFFEM
CANLIKILAQ
NT seq 1653 nt NT seq  +upstreamnt  +downstreamnt
atggcgacagccgagaagcagaaacacgacgggcgggtgaagatcggccactacatcctg
ggggacacgctgggggtcggcacgttcggcaaagtgaaggttggcaaacatgaattgact
gggcataaagttgctgtgaagatactcaatcgccagaagattcgaagcctcgatgtggtt
ggaaaaatccgcagagaaattcagaacctcaagcttttcaggcatcctcatataattaaa
ctgtaccaggtcatcagtacaccatctgatattttcatggtgatggaatatgtctcagga
ggagagctatttgattatatctgtaaaaatggaaggctcgatgaaaaagaaagtcgacgt
ctgttccaacagatcctttctggtgtggattattgtcacaggcatatggtggtccataga
gacttgaaacctgaaaacgtcctgcttgatgcacacatgaatgcaaagatagctgatttt
ggtctttcaaacatgatgtcagatggtgaatttttaagaacgagttgtggctcacccaac
tatgctgccccagaggtcatttcaggaagattgtatgcaggcccagaggtagacatatgg
agcagcggggttattctctatgctttattatgtggaacccttccatttgatgatgatcat
gtgccaactctttttaagaagatatgtgatgggatcttttatacccctcagtatttaaat
ccatccgtgattagccttttgaaacatatgctgcaggtggatcccatgaagcgggccaca
atcaaagatatcagggaacatgaatggtttaaacaagaccttccaaaatatctctttcct
gaggacccatcatatagttcaactatgattgatgatgaagccttaaaagaagtatgtgaa
aaatttgaatgctcagaagaggaggttctcagctgcctttataaccgaaatcaccaggac
cctttggcagtggcctaccacctcatcatagataacaggagaataatgaatgaagccaaa
gatttttacttggcgacaagcccacctgattcttttcttgatgatcaccatttgactcgg
ccccatcctgaaagagtaccattcttggttgctgaaacaccaagggcacgccatactctc
gatgaattaaatccacagaaatccaaacaccaaggtgtaagaaaagccaaatggcatttg
ggaattagaagtcaaagtcgaccaaatgatatcatggcagaagtttgtagagcaattaaa
caactggattatgaatggaaggttgtaaacccatattacttgcgtgttcgaaggaagaat
cctgtgacaagtacctactccaaaatgagtctacagttataccaagtggacagtagaaca
tacttactggatttccgtagtattgatgatgaaattactgaagccaaatccgggactgct
actccacaaagatcgggatccgttagcaactatcgatcttgtcagaggagtgattcggat
gctgaggctcaaggaaaatcctcagaagcttctcttacctcatcggtgacctcacttgac
tcttctcctgttgacttaactccaagacctggaagtcacacaatagagttttttgagatg
tgtgcgaatctaattaaaattcttgcacagtaa

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