KEGG   Equus caballus (horse): 100033860Help
Entry
100033860         CDS       T01058                                 

Gene name
TGFBR2, TBETA-RII, TGFBRII
Definition
transforming growth factor, beta receptor II (70/80kDa)
Orthology
K04388  
TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
Cytokine-cytokine receptor interaction
FoxO signaling pathway
Endocytosis
TGF-beta signaling pathway
Osteoclast differentiation
Hippo signaling pathway
Adherens junction
Chagas disease (American trypanosomiasis)
HTLV-I infection
Pathways in cancer
Transcriptional misregulation in cancer
Colorectal cancer
Pancreatic cancer
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100033860 (TGFBR2)
   04350 TGF-beta signaling pathway
    100033860 (TGFBR2)
   04390 Hippo signaling pathway
    100033860 (TGFBR2)
   04068 FoxO signaling pathway
    100033860 (TGFBR2)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100033860 (TGFBR2)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100033860 (TGFBR2)
  Cellular commiunity
   04520 Adherens junction
    100033860 (TGFBR2)
 Organismal Systems
  Development
   04380 Osteoclast differentiation
    100033860 (TGFBR2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100033860 (TGFBR2)
   05202 Transcriptional misregulation in cancers
    100033860 (TGFBR2)
   05210 Colorectal cancer
    100033860 (TGFBR2)
   05212 Pancreatic cancer
    100033860 (TGFBR2)
   05220 Chronic myeloid leukemia
    100033860 (TGFBR2)
  Infectious diseases
   05166 HTLV-I infection
    100033860 (TGFBR2)
   05142 Chagas disease (American trypanosomiasis)
    100033860 (TGFBR2)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     100033860 (TGFBR2)
Protein kinases [BR:ecb01001]
 Serine/threonine protein kinases: TKL group
  TGFBR2 family [OT]
   100033860 (TGFBR2)
Enzyme-linked receptors [BR:ecb01020]
 Receptor serine/threonine kinases
  Type II TGF-beta receptor
   100033860 (TGFBR2)
Cytokine receptors [BR:ecb04050]
 TGF-beta receptors
  Type II TGF-beta receptor
   100033860 (TGFBR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
16
AA seq 651 aa AA seqDB search
MVTDNDGAVKFPQFCKFCNVSSSICDNQKSCMSNCSITSRCEKPREVCVAVWRKNDKNIT
LETVCHDPKLTYHGFVLEDAASPKCIMKEKKVSGETFFMCSCSSDECNDHIIFSEVNNDI
MITDNNGAVKLPQLCKFCDVTSSTCDNQKSCMSNCSITSICEDPHEVCVAVWRKNDKNIT
LETVCHDPKLTYHGFVLEDAASPKCIMKEKKVSGETFFMCSCSSDECNDHIIFSEEYATN
NPDLLLVIFQVTGVSLLPPLGIAIAVIITFYCYRVHRQQKLSPSWETSKPRKLMEFSEHL
AIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAV
KIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQEY
LTRHVISWEDLRKLGSSLARGIAHLHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLC
DFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLWE
MTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCET
LTECWDHDPEARLTAQCVAERFSELEHMDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1956 nt NT seq  +upstreamnt  +downstreamnt
atggtcactgacaacgacggtgcagtcaagtttccacaattttgtaaattttgcaacgtg
agctcttccatctgtgacaaccagaaatcctgcatgagcaactgcagcatcacgtccaga
tgtgagaagccacgcgaagtctgtgtggctgtctggagaaagaatgataagaacataaca
ctagagacggtttgccatgaccccaagctcacctaccatggatttgttcttgaagatgct
gcttctccaaagtgtattatgaaggaaaaaaaagtgtctggcgagactttctttatgtgt
tcctgtagctctgatgagtgcaacgaccacatcatcttctcagaagttaataacgacatc
atgatcactgacaacaatggtgcagtcaagcttccacaactgtgtaaattttgtgacgtg
acgtcttccacctgtgacaatcagaaatcctgcatgagcaactgcagcatcacatccatc
tgtgaggatccacacgaagtctgtgtggctgtctggagaaagaatgataagaacataaca
ctagagacggtttgccatgaccccaagctcacctaccatggatttgttcttgaagatgct
gcttctccaaagtgtattatgaaggaaaaaaaagtgtctggcgagactttctttatgtgt
tcctgtagctctgatgagtgcaacgaccacatcatcttctcagaagaatatgccaccaac
aaccctgacttgttgttagtcatattccaagtgacaggcgtcagcctcctgccaccgctg
ggaattgccattgcggtcatcatcaccttctactgctaccgcgttcaccggcagcagaag
ctgagcccgtcctgggagaccagcaagccacggaagctcatggagttcagcgagcacctt
gccatcattctggaagacgaccgctccgacatcagctctacgtgtgccaacaatatcaac
cacaacacagagctgctgcccattgagctggacaccctggtggggaaaggtcgctttgct
gaggtctacaaggccaagctgaagcagaacacttcagagcagtttgagaccgtggcagtc
aagatctttccttatgaggagtacgcctcctggaagacagagaaggacattttttcagac
atcaacctgaagcatgagaacatactccagttcctgacagctgaggagcgaaagacagaa
ctgggaaagcaatattggctgatcaccgctttccatgccaagggcaacctacaggaatac
cttacacggcatgtcatcagctgggaggacctgcgcaagctaggcagctccctagcccgg
ggcattgctcacctgcacagtgaccacaccctgtgcgggaggcccaagatgcccattgtg
cacagggacctcaagagctccaacatcctcgtgaagaatgacctgacctgctgcctgtgt
gactttgggctttccctgcgtttggacccgaccctgtctgtggatgacctggccaacagt
gggcaggtgggaactgcaagatacatggccccagaagtcctggagtccaggatgaatttg
gagaatgttgagtccttcaagcagacagatgtctactccatggctctggtgctctgggaa
atgacatctcgctgtaacgcagtgggagaagtgaaagattatgagcctccatttggttcc
aaggtgcgggagcatccctgtgtcgaaagcatgaaggacaatgtcttgagagatcgagga
cgaccagaaattcccagctcctggctcaaccaccagggcatccagatggtgtgtgagact
ctgaccgagtgctgggaccacgacccggaggcccgtctcacggcccagtgcgtggcggaa
cgcttcagcgagctggagcacatggacagactctcggggaggagctgctccgaggagaag
attcccgaagacggctcgctgaacactaccaaatag

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