KEGG   Equus caballus (horse): 100033956
Entry
100033956         CDS       T01058                                 
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2 precursor
  KO
K05093  fibroblast growth factor receptor 2 [EC:2.7.10.1]
Organism
ecb  Equus caballus (horse)
Pathway
ecb01521  EGFR tyrosine kinase inhibitor resistance
ecb04010  MAPK signaling pathway
ecb04014  Ras signaling pathway
ecb04015  Rap1 signaling pathway
ecb04020  Calcium signaling pathway
ecb04144  Endocytosis
ecb04151  PI3K-Akt signaling pathway
ecb04550  Signaling pathways regulating pluripotency of stem cells
ecb04810  Regulation of actin cytoskeleton
ecb05200  Pathways in cancer
ecb05215  Prostate cancer
ecb05226  Gastric cancer
ecb05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100033956 (FGFR2)
   04014 Ras signaling pathway
    100033956 (FGFR2)
   04015 Rap1 signaling pathway
    100033956 (FGFR2)
   04020 Calcium signaling pathway
    100033956 (FGFR2)
   04151 PI3K-Akt signaling pathway
    100033956 (FGFR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100033956 (FGFR2)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100033956 (FGFR2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100033956 (FGFR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100033956 (FGFR2)
   05230 Central carbon metabolism in cancer
    100033956 (FGFR2)
  09162 Cancer: specific types
   05226 Gastric cancer
    100033956 (FGFR2)
   05215 Prostate cancer
    100033956 (FGFR2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100033956 (FGFR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100033956 (FGFR2)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ecb04090]
    100033956 (FGFR2)
   00536 Glycosaminoglycan binding proteins [BR:ecb00536]
    100033956 (FGFR2)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100033956 (FGFR2)
Protein kinases [BR:ecb01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   100033956 (FGFR2)
CD molecules [BR:ecb04090]
 Proteins
  100033956 (FGFR2)
Glycosaminoglycan binding proteins [BR:ecb00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100033956 (FGFR2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set Ig_5 ABC1 C2-set_2 V-set_CD47 DUF5527 Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 100033956
NCBI-ProteinID: NP_001157335
Ensembl: ENSECAG00000013960
VGNC: 18025
Position
1:11323858..11426681
AA seq 818 aa
MVSWGRFICLVVVTMATLSLARPSFNLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEL
RCLLRDAAMISWTKDGVHLGPSNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETVYF
MVNVTDAISSGDDEDDTDGSEDFVSESSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK
QQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTTKKPDFSSQPAVHKLT
KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRD
KLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMK
MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMT
FKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKK
TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG
HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQY
SPSYPDTRSSCSSGDDSVFLCYDPCLPQYPHINGSVKT
NT seq 2457 nt   +upstreamnt  +downstreamnt
atggtcagctggggtcgcttcatctgcctggttgtggtcaccatggcaaccttgtccctg
gcccggccctccttcaatttagttgaggataccacattagagccggaagagccaccaacc
aaataccaaatctcccaaccagaagtgtacgtggctgcgcccggggaatcgctagagttg
cgctgcctgttgagagatgccgccatgatcagttggactaaggatggggtacacttgggg
cccagcaataggacagtgcttattggggagtacttgcagataaaaggtgccacgcctaga
gactccggcctctatgcttgtactgctgctaggaccgtagacagtgagactgtctacttc
atggtcaatgtcacagatgccatctcatccggagatgacgaggacgacacagatggctcc
gaggattttgtcagtgagagcagtaacaacaagagagcaccatactggaccaacacagaa
aagatggaaaaacggctgcatgccgtccccgcagccaatactgtcaagtttcgctgtcca
gctggggggaatccaacaccaactatgaggtggctgaaaaacgggaaagaatttaagcag
gagcatcgcatcggaggatataaggtacgaaaccagcactggagccttattatggaaagc
gtggtcccatccgacaaaggcaattacacctgtgtggtggagaatgagtacgggtccatc
aatcacacgtaccacctcgatgttgttgagcgatcaccacaccggcccatcctccaagct
ggactgccagcaaatgcctccaccgtggtgggaggcgatgtggagtttgtctgcaaagtt
tacagcgatgcccagccccacatccagtggatcaaacatgtggaaaagaacggcagtaaa
tacgggcccgacgggctgccctacctcaaagttctgaagcactcggggataaatagttcc
aatgcagaagtgctggctctgttcaatgtgactgaggcggatgctggggagtatatatgt
aaggtctccaattatatagggcaggccaaccagtctgcctggctcactgtcctgccaaaa
cagcaagctcccgtaagagaaaaggagattacagcttccccagactacctggagatagcc
atttactgcataggggtcttcttaattgcctgtatggtggtgacggtcatcctgtgccga
atgaagaccacgaccaagaagccagacttcagcagccagccggctgtgcacaagctgacc
aagcgcatccccttgcggagacaggtaacagtttctgccgagtccagctcctccatgaac
tccaacaccccactggtgaggataacaacgcgcctctcctcgacagcagacacccccatg
ctggcgggggtctccgagtatgaactgccagaagatcccaaatgggagtttccgagagat
aagctgacgctgggcaaacccctgggggaaggttgctttgggcaagtggtcatggctgaa
gcagtgggaatcgacaaagagaagcccaaggaagcagtcactgtggccgtgaagatgttg
aaagatgatgccacggagaaggacctttctgatctggtgtcagagatggagatgatgaaa
atgattggaaaacacaaaaacatcataaatctccttggagcctgtactcaggatggacca
ctctacgtcatagttgagtatgcctcgaagggtaacctccgtgagtacctccgagcccgg
aggccgcctgggatggagtactcctatgacattaaccgcgttcccgaggagcagatgact
ttcaaagacttggtgtcatgcacctaccagctggccagaggcatggagtacctggcttcc
caaaaatgtattcatcgagatttagcagccagaaatgttttggtaacagaaaacaatgtg
atgaaaatagcagactttggactggccagagatatcaacaatatagactattacaaaaag
accacaaatgggcgacttccggtcaagtggatggctccagaagccctttttgatagagtg
tacacccatcagagtgatgtctggtccttcggggtgttgatgtgggagatcttcacttta
gggggctcgccttacccagggattcccgtggaggaactttttaagctgcttaaggaagga
cacaggatggataagccggcaaactgcaccaacgaactgtacatgatgatgagggactgt
tggcatgcagtgccctcccagaggccgacgttcaagcagttggtggaagacttggaccga
attctcactctcacgaccaatgaggaatacttggacctcagtcagcctctcgaacagtat
tctcctagttaccctgacacaaggagttcatgttcttcaggagatgattctgttttcttg
tgttacgacccatgccttcctcagtatccacatataaacggcagtgttaaaacatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (12)   
   RefSeq(pep) (12)   
DNA sequence (18)   
   RefSeq(nuc) (12)   
   GenBank (3)   
   EMBL (3)   
Protein domain (14)   
   Pfam (14)   
All databases (72)   

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