KEGG   Equus caballus (horse): 100034159Help
Entry
100034159         CDS       T01058                                 

Gene name
PRKAA2
Definition
protein kinase, AMP-activated, alpha 2 catalytic subunit
Orthology
K07198  
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
Organism
ecb  Equus caballus (horse)
Pathway
FoxO signaling pathway
Regulation of autophagy
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Circadian rhythm
Insulin signaling pathway
Adipocytokine signaling pathway
Oxytocin signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    100034159 (PRKAA2)
   04151 PI3K-Akt signaling pathway
    100034159 (PRKAA2)
   04152 AMPK signaling pathway
    100034159 (PRKAA2)
   04150 mTOR signaling pathway
    100034159 (PRKAA2)
 Cellular Processes
  Transport and catabolism
   04140 Regulation of autophagy
    100034159 (PRKAA2)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100034159 (PRKAA2)
   04920 Adipocytokine signaling pathway
    100034159 (PRKAA2)
   04921 Oxytocin signaling pathway
    100034159 (PRKAA2)
  Environmental adaptation
   04710 Circadian rhythm
    100034159 (PRKAA2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100034159 (PRKAA2)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100034159 (PRKAA2)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     100034159 (PRKAA2)
Protein kinases [BR:ecb01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   100034159 (PRKAA2)
Mitochondrial biogenesis [BR:ecb03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100034159 (PRKAA2)
  Mitophagy factors
   Other mitophagy factors
    100034159 (PRKAA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
2p18-p17
AA seq 552 aa AA seqDB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPTYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSTMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSLDSVTAESHSLSGSLTGSWTGSTLSSAPPRLGSHTMDFF
EMCASLITTLAR
NT seq 1659 nt NT seq  +upstreamnt  +downstreamnt
atggcagagaagcagaagcacgacgggcgggtgaagatcgggcactacgtgctgggggac
acgctgggcgtcggcaccttcggcaaagtgaagattggagaacatcaattgacaggccat
aaagtggcagttaaaatcttaaatagacagaagattcgcagtttagatgtcgttggaaaa
ataaaacgagaaattcaaaatctaaaactctttcgtcaccctcatattatcaaactatac
caggtgatcagcactccaacagatttttttatggtaatggaatatgtgtctggtggtgaa
ttatttgactacatctgtaaacatggacgggttgaagagatggaagccaggcggctcttt
cagcagattctgtccgctgtggattactgtcacaggcatatggttgttcatcgagacctg
aaaccagagaacgtgctgttggatgcacaaatgaatgccaagatagctgattttggatta
tctaatatgatgtcagatggtgaatttctgcgaactagttgtggatctccaaattatgca
gcacctgaagtcatctcaggcagattgtatgcaggtccagaagttgatatctggagctgt
ggtgtgattttgtatgctcttctttgtggcaccctcccatttgatgatgagcatgtacct
acgttgtttaagaagatccgagggggtgttttttatatcccagaatatcttaatcgttct
gttgccactctcctgatgcatatgctgcaggttgaccccctgaaacgagcaactatcaaa
gacataagagagcatgaatggtttaaacaagatttgcccacttacttatttcctgaggac
ccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtgtgtgaaaaattt
gagtgtacagaatcagaagtaatgaacagtttatatagtggtgaccctcaagaccagctt
gcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctcgagtcccccaactggttcttttatggatgatagtaccatgcatattccc
ccaggcctgaaacctcatccagaaaggatgccacctcttatagcagacagccctaaagca
agatgtccattggatgcactgaatacaactaaacccaaatctttagctgtgaaaaaagcc
aagtggcatcttggaatccgaagtcagagcaaaccgtatgacattatggctgaagtttac
cgagctatgaaacagctggattttgaatggaaggtagtgaatgcataccatcttcgtgta
agaagaaaaaatccagtgactggcaattatgtgaaaatgagcttacaactttacctggtt
gacaatagaagctatcttttggactttaaaagcattgatgatgaggtggtggagcagagg
tctggttcctcaacacctcagcgttcctgttctgctgctggcttacacagaccaagatcg
agtttagattctgtaactgcggagagccattcgttgtctggctctctcactggctcctgg
acgggaagcaccttgtcctcagctccacctcgcttaggcagtcacaccatggatttcttt
gaaatgtgtgccagtctgatcactactttagcccgttga

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