KEGG   Equus caballus (horse): 100050532Help
Entry
100050532         CDS       T01058                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100050532 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100050532 (PIK3CG)
   04015 Rap1 signaling pathway
    100050532 (PIK3CG)
   04012 ErbB signaling pathway
    100050532 (PIK3CG)
   04370 VEGF signaling pathway
    100050532 (PIK3CG)
   04630 Jak-STAT signaling pathway
    100050532 (PIK3CG)
   04668 TNF signaling pathway
    100050532 (PIK3CG)
   04066 HIF-1 signaling pathway
    100050532 (PIK3CG)
   04068 FoxO signaling pathway
    100050532 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    100050532 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    100050532 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    100050532 (PIK3CG)
   04152 AMPK signaling pathway
    100050532 (PIK3CG)
   04150 mTOR signaling pathway
    100050532 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100050532 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    100050532 (PIK3CG)
  Cell communication
   04510 Focal adhesion
    100050532 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100050532 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    100050532 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    100050532 (PIK3CG)
   04660 T cell receptor signaling pathway
    100050532 (PIK3CG)
   04662 B cell receptor signaling pathway
    100050532 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    100050532 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    100050532 (PIK3CG)
   04670 Leukocyte transendothelial migration
    100050532 (PIK3CG)
   04062 Chemokine signaling pathway
    100050532 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    100050532 (PIK3CG)
   04915 Estrogen signaling pathway
    100050532 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    100050532 (PIK3CG)
   04917 Prolactin signaling pathway
    100050532 (PIK3CG)
   04921 Oxytocin signaling pathway
    100050532 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    100050532 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100050532 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100050532 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100050532 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    100050532 (PIK3CG)
   04722 Neurotrophin signaling pathway
    100050532 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100050532 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    100050532 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100050532 (PIK3CG)
   05205 Proteoglycans in cancer
    100050532 (PIK3CG)
   05203 Viral carcinogenesis
    100050532 (PIK3CG)
   05210 Colorectal cancer
    100050532 (PIK3CG)
   05212 Pancreatic cancer
    100050532 (PIK3CG)
   05214 Glioma
    100050532 (PIK3CG)
   05221 Acute myeloid leukemia
    100050532 (PIK3CG)
   05220 Chronic myeloid leukemia
    100050532 (PIK3CG)
   05218 Melanoma
    100050532 (PIK3CG)
   05211 Renal cell carcinoma
    100050532 (PIK3CG)
   05215 Prostate cancer
    100050532 (PIK3CG)
   05213 Endometrial cancer
    100050532 (PIK3CG)
   05222 Small cell lung cancer
    100050532 (PIK3CG)
   05223 Non-small cell lung cancer
    100050532 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100050532 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100050532 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100050532 (PIK3CG)
   05166 HTLV-I infection
    100050532 (PIK3CG)
   05162 Measles
    100050532 (PIK3CG)
   05164 Influenza A
    100050532 (PIK3CG)
   05161 Hepatitis B
    100050532 (PIK3CG)
   05160 Hepatitis C
    100050532 (PIK3CG)
   05169 Epstein-Barr virus infection
    100050532 (PIK3CG)
   05146 Amoebiasis
    100050532 (PIK3CG)
   05145 Toxoplasmosis
    100050532 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    100050532 (PIK3CG)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100050532 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
4
AA seq 1102 aa AA seqDB search
MELENYEQPVVLREDNRRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRNSKTPETALLH
VAXHGNVEQMKAQVWLRALETSGAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHVVQRHAPSEDTVAFQQQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDQVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKVRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASADTPSSESKGKVQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLAKREVWDQSALDVGLTMQLLDCSFPDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALVRFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGMAMLHDFTQQVQVIEVLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKRADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKERCPLEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggaaaactatgaacagcccgtggttctgagagaggacaaccgccgcaggcgc
cggaggatgaagccgcgcagcgccgcggccagcctgtcctccatggagctcatccccatc
gagttcgtgctgcccacgagccagcgcaacagcaagacccccgaaacggcgctgctgcac
gtggctnggcacggcaacgtggagcagatgaaggcgcaggtgtggctgcgcgcgctggag
accagcggagcagcggacttctaccaccggctggggccggaccacttcctcctgctctac
cagaagaaggggcagtggtacgagatctacgacaagtaccaggtggtgcagaccctggac
tgcctgcgctactggaaggtgctgcacaggagcccaggccagatccacgtggtgcaacgg
cacgcgccctcggaggacacggtggccttccagcagcagctcacagccctgattggctat
gacgtcaccgatgtcagcaacgtgcacgacgacgagctcgagttcacacgccgccgcctg
gtcaccccgcgcatggccgaggtggccggccgtgaccccaagctctacgccatgcacccc
tgggtgacgtccaagcccctgccggagtacctgttgaagaagattaccaacaactgcatc
ttcattgtcattcatcgcagcaccaccagccagaccatcaaggtctcggcagatgatacc
ccaggcaccatcctccagagcttcttcaccaagatggccaagaagaagtctctgatggat
atcccggaaagccaaaacgaacaggactttgtgctgcgcgtctgtggccgggatgagtac
ctggtgggtgaaacgcccatcaaaaactttcagtgggtgaggcagtgcctcaagaatggg
gaggagattcacctggtgcttgacactcctccggacccagccctggaccaggtgaggaaa
gaagagtggccactggtggatgactgcacgggagtcaccggctaccatgagcagctgacc
atccacgggaaggaccatgagagcgtgttcaccgtgtccctgtgggactgtgaccggaag
ttcagggttaaagtcagaggcattgatatcccggtcctgccccggaacgctgacctcacg
gtgtttgtggaggcaaacatccagcatgggcagcaagtcctttgccaaaggagaaccagc
cccaaacccttcacggaggaggtgctctggaacgtgtggcttgaattcagcatcaaaatc
aaagacttacccaaaggggctcttctgaacctccagatctactgtggcaaagctccagcg
ctgtctggcaaggcctctgcagacactcccagttctgagtccaaaggcaaagttcagctt
ctctattatgtgaacctgctgctgatagaccaccggttcctcctgcgccacggggaatac
gtgctccacatgtggcagttatccgggaagggcgaagatcaagggagcttcaacgctgac
aagctcacctctgcaaccaacccggacaaggagaactccatgtccatctccattctcctg
gacaattactgtcacccaatagccttgcctaagcatcggcccacccctgatcccgaaggg
gaccgggttcgagccgaaatgcccaaccagcttcggaaacaactggaggcaatcatagcc
actgacccacttaaccctctcacagcagaagacaaagaattgctctggcatttcagatat
gaaagccttaagcatccaaaagcatatcctaagctatttagctcagtgaaatggggacag
caagaaattgtggccaaaacttatcagttgttagccaaaagggaggtatgggatcaaagt
gcattggatgttgggctaacgatgcaactcctggactgcagctttccagatgaaaatgta
agagccattgcggtccagaaactggagagcttggaggacgatgacgttctgcactacctg
ctacagctggtccaggctgtgaagtttgaaccataccatgacagtgcccttgtcagattt
ctgctgaagcgtggcttaagaaacaaaagaattggtcacttcttgttttggttcttgcga
agtgagatagcccagtccaggcactaccagcagaggttcgctgtgatcctggaggcctac
ctgagaggctgtggtatggccatgctgcacgactttacccagcaagtccaagtcatcgag
gtgttacagaaagtcaccattgacattaaatcgctctcagctgaaaagtatgacgtcagt
tctcaagttatatcgcaacttaagcaaaagcttgaaaacctgcagaatttgaatctccct
caaagctttagagttccctatgatcctgggctgaaagcaggagcgctggtgattgaaaaa
tgcaaagtgatggcctccaagaagaagcccctgtggcttgagtttaaacgtgccgaccct
acagctctctcaaatgaaaccattggaattatctttaaacatggagacgatctgcgccaa
gacatgcttattttacagattctaaggatcatggagtctatctgggagactgaatccttg
gatctgtgcctcctgccatatggttgcatttcgactggggacaaaattggaatgatcgag
attgtaaaagatgccacaacaattgccaaaattcagcaaagcacagtgggcaacacggga
gcatttaaggatgaagtcctgagtcactggctcaaagagagatgccctcttgaagaaaag
tttcaggcagcagtggagagatttgtttattcctgtgctggctactgtgtggcaaccttt
gttctcggaataggcgacaggcacaatgataatattatgatcacagagacgggaaatcta
tttcatattgactttgggcacattcttgggaattacaaaagtttcctgggcattaataaa
gaaagagtgccgtttgtgctaaccccagacttcctgtttgtgatgggaacttctggaaag
aagacaagcctccacttccagaaatttcaggatgtctgtgtgaaggcttatctagccctt
cggcatcacacaaacctactgatcatcctcttctccatgatgctgatgacggggatgccc
cagctaacaagcaaagaagacattgaatatattcgggatgccctaacagtggggaaaaat
gaggaggatgcgaagaagtattttctcgatcagattgaagtttgcagagacaaaggatgg
actgtgcagtttaactggttcctacatcttgttcttggcatcaaacaaggagagaaacat
tcagcctaa

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