KEGG   Equus caballus (horse): 100051485Help
Entry
100051485         CDS       T01058                                 

Gene name
PLCB4
Definition
phospholipase C, beta 4
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100051485 (PLCB4)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100051485 (PLCB4)
   04310 Wnt signaling pathway
    100051485 (PLCB4)
   04020 Calcium signaling pathway
    100051485 (PLCB4)
   04070 Phosphatidylinositol signaling system
    100051485 (PLCB4)
   04022 cGMP - PKG signaling pathway
    100051485 (PLCB4)
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    100051485 (PLCB4)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100051485 (PLCB4)
   04062 Chemokine signaling pathway
    100051485 (PLCB4)
  Endocrine system
   04911 Insulin secretion
    100051485 (PLCB4)
   04912 GnRH signaling pathway
    100051485 (PLCB4)
   04915 Estrogen signaling pathway
    100051485 (PLCB4)
   04921 Oxytocin signaling pathway
    100051485 (PLCB4)
   04918 Thyroid hormone synthesis
    100051485 (PLCB4)
   04919 Thyroid hormone signaling pathway
    100051485 (PLCB4)
   04916 Melanogenesis
    100051485 (PLCB4)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100051485 (PLCB4)
   04270 Vascular smooth muscle contraction
    100051485 (PLCB4)
  Digestive system
   04970 Salivary secretion
    100051485 (PLCB4)
   04971 Gastric acid secretion
    100051485 (PLCB4)
   04972 Pancreatic secretion
    100051485 (PLCB4)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100051485 (PLCB4)
  Nervous system
   04724 Glutamatergic synapse
    100051485 (PLCB4)
   04725 Cholinergic synapse
    100051485 (PLCB4)
   04728 Dopaminergic synapse
    100051485 (PLCB4)
   04726 Serotonergic synapse
    100051485 (PLCB4)
   04720 Long-term potentiation
    100051485 (PLCB4)
   04730 Long-term depression
    100051485 (PLCB4)
   04723 Retrograde endocannabinoid signaling
    100051485 (PLCB4)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100051485 (PLCB4)
  Environmental adaptation
   04713 Circadian entrainment
    100051485 (PLCB4)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100051485 (PLCB4)
   05016 Huntington's disease
    100051485 (PLCB4)
  Infectious diseases
   05146 Amoebiasis
    100051485 (PLCB4)
   05142 Chagas disease (American trypanosomiasis)
    100051485 (PLCB4)
   05143 African trypanosomiasis
    100051485 (PLCB4)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100051485 (PLCB4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
22
AA seq 1206 aa AA seqDB search
MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVL
ECSLINSVRLGASPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPE
VTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKTKGLISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQALESHPLEPGRPLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSM
MEAGESAAPVSILEDDNEEEIESADQEEEAHPEYKFGNELSADDLGHKEAVANSVKKASD
DLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNI
HYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNRLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNEKKGKANTAKANVTPQ
SSSELRPTTTAALGPGMEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAK
EHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLISAHEQQTQQLKLS
HDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEFLEKQNEQLLKSCHAVSQTQGEGDAADGEIGSRDGPQTSNSSM
KLQNAN
NT seq 3621 nt NT seq  +upstreamnt  +downstreamnt
atggccaaaccttatgaatttaactggcagaaggaagtgccttcctttttgcaagaagga
gcagtttttgacagatatgaagaggaatcttttgtgtttgaacccaactgcctcttcaaa
gtggatgagtttggcttctttctgacctggagaagtgaaggcaaggaaggacaagtgcta
gaatgttccctcatcaacagtgttcggttgggagcctcaccaaaggatcccaaaatcctg
gctgctcttgaagctgttggaaaatcagaaaatgatctggaagggcggatagtttgtgtc
tgcagtggtacagatctggtgaacatcagtttcacgtacatggtggctgaaaatccagaa
gtaacaaagcaatgggtcgaaggcctgagatcaatcatacacaacttcagggccaacaac
gtcagtccaatgacatgcctcaagaaacactggatgaaattggcatttatgaccaacaca
aatggtaaaattccagttaggagtattactagaacctttgcctcggggaaaacagaaaag
gtgatctttcaagcgctcaaggaattaggtcttcccagtggaaagaatgatgaaatcgag
cctgcggcatttacttatgaaaagttctatgaactgacgcaaaagatttgtcctcggaca
gatatagaggatctttttaaaaaaatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcgactgaatgagattttattt
ccattttatgatgctaaaagggcaatgcagatcattgagatgtatgagcccgatgaagat
ttgaagacaaaaggcctcatatcaagtgatgggttttgcagatatctgatgtcagatgaa
aatgccccagtcttcctagatcgtttagaactttaccaagaaatggaccatcctctggct
cactacttcatcagttcttcccataacacctatctcaccggccggcagtttggcgggaag
tcttcagtagaaatgtacagacaggtcctcctggctggttgcagatgtgttgaacttgac
tgttgggatggaaaaggtgaagaccaagaaccgataataactcatggaaaagcaatgtgt
acagatatcctttttaaggatgttattcaagccatcaaggaaactgcgtttgtcacatcc
gaatatcctgtaattctctcctttgaaaatcactgcagcaaatatcaacagtacaagatg
tccaaatattgcgaagatctatttggggacctcctgttgaaacaagcacttgaatcgcat
ccactcgaaccaggcaggcccttgccatcccccaatgacctcaaaagaaaaatactcatc
aaaaataaacggctgaaacctgaagttgaaaaaaaacagctcgaagctttgaaaagcatg
atggaagctggagaatctgctgccccagttagcatcttagaggatgataatgaagaggaa
atagaaagtgctgaccaagaggaggaagctcaccctgaatacaaatttggaaatgaactt
tctgctgatgacctgggtcacaaggaagctgttgcaaatagtgtcaagaaggcttcagat
gaccttgaacatgaaaacaacaaaaagggcctggttactgtagaagatgagcaggcgtgg
atggcgtcctataaatacgtgggtgctaccactaacatccatccctatctgtccacaatg
atcaactatgcacagcccgtgaaatttcaaggtttccatgtcgctgaagaacgcaatatt
cattataacatgtcttcttttaatgagtcagtcggtctaggctacctgaagacacatgcg
attgaatttgtgaattataacaaacgacaaatgagtcgtatttaccccaagggaggccga
gtcgattccagtaattacatgcctcagattttctggaacgctggctgccagatggtttca
ctgaactatcaaaccccagatttagcgatgcaattgaatcagggaaaatttgagtataat
ggatcctgcgggtaccttctcaaaccagatttcatgagacgacccgatcgaacatttgat
cccttctctgaaactcctgtcgatggggtcattgcagccacttgctcagtgcaggtcata
tcaggtcagttcttgtcagacaagaaaattggcacatatgtagaagttgacatgtatggg
ttgcccacggacactatacgtaaggagttccgaactcgcatggtgatgaacaatggactc
aatccagtttacaatgaagaatcatttgtatttcggaaggtaatcctccctgacctggca
gtcttgagaatagcagtgtatgatgacaacaacaggctgattggccagaggattcttcca
ctggatggcctccaagcaggttatcggcacatatcccttcgaaatgagggaaataaacca
ctatcactgccaacgattttctgcaatattgttcttaaaacatatgtgcctgatggattt
ggagatattgtagatgctttatcagatccaaagaaatttctttccattacggaaaagaga
gcagaccaaatgagagctatgggcattgaaactagtgacatagctgatgtgcccagtgac
acttctaagaatgagaagaaaggaaaggccaacactgccaaagcaaatgtgaccccacag
agcagctccgagctcagaccaaccaccacagccgccctggggcctggcatggaagccaag
aaaggtattgaacttatccctcaagtaaggatagaagatttaaagcagatgaaggcttac
ttgaagcatttaaagaaacaacagaaggagctaaattctttaaagaagaaacatgcaaag
gaacacagtaccatgcaaaagctacactgcacgcaagttgacaaaatcgtggcacagtat
gacaaagagaagtcgactcatgagaaaatcctagagaaggcaatgaagaagaagggggga
agtaattgtcttgaaatgaaaaaagaaacagaaattaaaattcagacactgacatcagat
cacaaatctaaggtcaaagagattgtggcccagcacacaaaggagtggtcagaaatgatc
aacacccacagtgctgaggagcaagaaatccgggacctgcacctcagccagcagtgcgag
ctgctgagaaagctcctgatcagtgcccacgagcagcaaacccagcagctaaaactgtcc
catgacagggaaagcaaagaaatgagagcacaccaggctaagatttctatggaaaatagc
aaggccatcagccaagataaatctatcaagaataaagcagaacgggaaaggcgagtcagg
gagttaaacagcagcaatactaaaaagtttctggaagaaagaaagagacttgcaatgaaa
cagtccaaagaaatggatcagctgaaaaaagtccagcttgaacacctagaattcctagag
aaacagaatgagcagcttttgaaatcctgtcatgcagtgtcccaaacgcaaggcgaagga
gatgcagcagatggtgaaattggaagccgagatggaccgcagaccagcaacagtagtatg
aaactccaaaacgcaaactga

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