KEGG   Equus caballus (horse): 100051558Help
Entry
100051558         CDS       T01058                                 

Gene name
PLCB1
Definition
phospholipase C, beta 1 (phosphoinositide-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100051558 (PLCB1)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100051558 (PLCB1)
   04310 Wnt signaling pathway
    100051558 (PLCB1)
   04020 Calcium signaling pathway
    100051558 (PLCB1)
   04070 Phosphatidylinositol signaling system
    100051558 (PLCB1)
   04022 cGMP - PKG signaling pathway
    100051558 (PLCB1)
 Cellular Processes
  Cell communication
   04540 Gap junction
    100051558 (PLCB1)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100051558 (PLCB1)
   04062 Chemokine signaling pathway
    100051558 (PLCB1)
  Endocrine system
   04911 Insulin secretion
    100051558 (PLCB1)
   04912 GnRH signaling pathway
    100051558 (PLCB1)
   04915 Estrogen signaling pathway
    100051558 (PLCB1)
   04921 Oxytocin signaling pathway
    100051558 (PLCB1)
   04918 Thyroid hormone synthesis
    100051558 (PLCB1)
   04919 Thyroid hormone signaling pathway
    100051558 (PLCB1)
   04916 Melanogenesis
    100051558 (PLCB1)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100051558 (PLCB1)
   04270 Vascular smooth muscle contraction
    100051558 (PLCB1)
  Digestive system
   04970 Salivary secretion
    100051558 (PLCB1)
   04971 Gastric acid secretion
    100051558 (PLCB1)
   04972 Pancreatic secretion
    100051558 (PLCB1)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100051558 (PLCB1)
  Nervous system
   04724 Glutamatergic synapse
    100051558 (PLCB1)
   04725 Cholinergic synapse
    100051558 (PLCB1)
   04728 Dopaminergic synapse
    100051558 (PLCB1)
   04726 Serotonergic synapse
    100051558 (PLCB1)
   04720 Long-term potentiation
    100051558 (PLCB1)
   04730 Long-term depression
    100051558 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    100051558 (PLCB1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100051558 (PLCB1)
  Environmental adaptation
   04713 Circadian entrainment
    100051558 (PLCB1)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100051558 (PLCB1)
   05016 Huntington's disease
    100051558 (PLCB1)
  Infectious diseases
   05146 Amoebiasis
    100051558 (PLCB1)
   05142 Chagas disease (American trypanosomiasis)
    100051558 (PLCB1)
   05143 African trypanosomiasis
    100051558 (PLCB1)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100051558 (PLCB1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
22
AA seq 1115 aa AA seqDB search
MITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKL
QVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCP
RPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPN
NSLAKKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLA
GNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFK
TSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYK
ILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCK
KSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKSKNRSFEMSSFVETKGLEQLTK
SPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYE
YNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDM
FGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAVYEEGGKCIGHRI
LPVQAIRPGYHYISLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLME
QRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTSLTPKPPSQALHS
QPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKT
TDLIKEHTTKYNEIQNDYLRRRAALEKTAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEM
TQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQSNQLKKLKEIC
EKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQ
EKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHSS
APPSLASDPGKLNHRPPSSEELEGDNPGKEFDTPL
NT seq 3348 nt NT seq  +upstreamnt  +downstreamnt
atgataacggtggtatatgggcctgacttagttaacatctcccatttgaacctcgtggct
ttccaagaagaagtggccaaggaatggacaaatgaggtttttagtttggcaacaaacctg
ctggcccaaaacatgtccagggacgcatttctggaaaaagcctatactaaacttaagctg
caagtcactccagaagggcgcattcctctcaaaaacatataccgcttgttttcagcagac
cggaagcgagttgaaactgctttagaggcttgtagtcttccatcttcgaggaatgattca
atacctcaagaagatttcactccagaagtgtacagagttttcctgaacaacctttgccct
cgacctgaaattgataacatcttttccgaatttggtgccaaaagcaaaccataccttact
gttgatcagatgatggattttatcaatcttaaacagcgagatcctcggctaaatgaaata
ctttacccacctttaaagcaagaacaagtccaagtattgattgagaagtatgaacccaac
aatagtctcgccaaaaaaggacagatatcagtggacggattcatgcgctatctgagtgga
gaagaaaatggagtcgtttcacctgagaaactggatttgaatgaagatatgtctcagcct
ctttctcactatttcattaattcctcacacaacacctacctcacagctggccagctggct
ggaaactcctccgtcgagatgtaccgccaagtgcttctgtctggttgtcgctgcgtagag
ttggactgctggaagggacggaccgcagaagaggaaccagtcatcacccatgggttcacc
atgacaactgaaatatccttcaaggaagtgatagaagcaattgctgagtgtgcatttaag
acttcaccttttccaattctgctttcatttgagaaccacgtggactccccaaagcagcaa
gccaagatggcggagtattgccggctcatctttggggacgcccttctcatggaaccactg
gaaaaatacccactggaatctggagttcctcttccaagccctatggatttaatgtataaa
attttggtgaaaaataaaaagaagtcacacaagtcatcagaaggaagtggcaaaaagaag
ctctcggaacaagcctccaacacgtacagcgactcctccagtgtgttcgagccctcgtct
ccgggagccggggaagctgacacagagagcgacgatgatgacgatgacgatgactgtaaa
aaatcttcaatggatgagggcactgctgggagcgaggccatggccacagaagagatgtct
aacctggtgaactatattcagccagtcaagtttgagtcatttgaaatttcaaaaagtaaa
aatagaagttttgaaatgtcttccttcgtggaaaccaaaggacttgagcaacttacgaag
tctccagtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaaggg
acacgcgtggattcatccaactacatgcctcagctcttctggaacgcaggttgccaaatg
gttgcccttaatttccaaacagtggacctggctatgcaaataaatatggggatgtatgaa
tataacgggaagagtggctacagattaaagccagagttcatgaggagacctgataagcat
tttgatccattcactgaaggcatcgttgatgggatagtggccaacactttatctgttaag
attatttccggtcagtttctttctgataagaaagttgggacttacgtagaagtggacatg
ttcggtttgccggtggacacaaggaggaaggcattcaagaccaagacatcacaaggaaac
gctgtcaatcccgtctgggaagaagaacccattgtcttcaaaaaggtggtccttccttct
ctggcctgtttgaggatagcagtttatgaagaaggaggcaaatgtatcggtcaccggatc
ttgccagtgcaagcaattcgaccaggctatcactacatctctctgaggaatgagaggaac
cagcctctgatgctaccagctgtctttgtctacatagaggtgaaagactatgtcccagat
acatatgcagatgtgattgaagctttgtcaaatccaatccgctatgtgaatctgatggag
cagagagctaagcaactggctgctttgacactggaagatgaagaagaagtgaagaaagag
gctgatcctggggaaacaccatcggaggctccgagtgaagccaggacaactccagcagaa
aacggagtgaatcacactacatccctgacacctaaacctccctcccaggctctccacagc
cagccagctccaggttctgtaaaggcaccggccaaaacagaagatctcattcagagtgtt
ttaacagaagtggaagcgcagactattgaagagctaaagcaacagaaatcgttcgtgaaa
cttcaaaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaaacc
actgaccttatcaaagagcacactacaaaatataatgaaattcagaatgactacttgaga
aggagggcagctttggaaaagacagccaaaaaggatagtaagaaaaaatcggaacccagc
agtcctgaccatggttcatcgacaattgagcaagaccttgctgccctggatgctgaaatg
acccaaaagttaatagacttgaaggacaaacagcagcagcagctgcttaatcttcgacaa
gaacagtattatagtgaaaaataccagaagcgagaacatattaagttgcttattcaaaaa
ttgacggatgttgctgaagaatgtcagagcaatcagttaaagaagctcaaagaaatctgt
gagaaagagaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagataaca
gaagctaaatccaaagacaaaagccagatggaagaggaaaagacagagatgatccggtca
tacatccaggaggtggtgcagtacatcaagaggttagaagaggcgcaaagtaaacgacaa
gaaaaactggtagagaaacacaaggagatacgtcagcagatcctggatgaaaagcccaag
ctgcaggtggagctggagcaagagtaccaagacaagttcaaaagactacccctggagatt
ttggagttcgtgcaggaagccatgaaagggaaaatcagtgaagacagcaatcacagttct
gcccctccctctctggcctcagaccctggcaaactgaaccacagacctccctccagtgag
gagctggaaggagacaacccaggaaaagagtttgataccccgctgtga

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