KEGG   Equus caballus (horse): 100051623Help
Entry
100051623         CDS       T01058                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100051623 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100051623 (PIK3CD)
   04015 Rap1 signaling pathway
    100051623 (PIK3CD)
   04012 ErbB signaling pathway
    100051623 (PIK3CD)
   04370 VEGF signaling pathway
    100051623 (PIK3CD)
   04630 Jak-STAT signaling pathway
    100051623 (PIK3CD)
   04668 TNF signaling pathway
    100051623 (PIK3CD)
   04066 HIF-1 signaling pathway
    100051623 (PIK3CD)
   04068 FoxO signaling pathway
    100051623 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    100051623 (PIK3CD)
   04024 cAMP signaling pathway
    100051623 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    100051623 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    100051623 (PIK3CD)
   04152 AMPK signaling pathway
    100051623 (PIK3CD)
   04150 mTOR signaling pathway
    100051623 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100051623 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    100051623 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    100051623 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100051623 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    100051623 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    100051623 (PIK3CD)
   04660 T cell receptor signaling pathway
    100051623 (PIK3CD)
   04662 B cell receptor signaling pathway
    100051623 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    100051623 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    100051623 (PIK3CD)
   04670 Leukocyte transendothelial migration
    100051623 (PIK3CD)
   04062 Chemokine signaling pathway
    100051623 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    100051623 (PIK3CD)
   04915 Estrogen signaling pathway
    100051623 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    100051623 (PIK3CD)
   04917 Prolactin signaling pathway
    100051623 (PIK3CD)
   04921 Oxytocin signaling pathway
    100051623 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    100051623 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100051623 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100051623 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100051623 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    100051623 (PIK3CD)
   04722 Neurotrophin signaling pathway
    100051623 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100051623 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    100051623 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100051623 (PIK3CD)
   05205 Proteoglycans in cancer
    100051623 (PIK3CD)
   05203 Viral carcinogenesis
    100051623 (PIK3CD)
   05210 Colorectal cancer
    100051623 (PIK3CD)
   05212 Pancreatic cancer
    100051623 (PIK3CD)
   05214 Glioma
    100051623 (PIK3CD)
   05221 Acute myeloid leukemia
    100051623 (PIK3CD)
   05220 Chronic myeloid leukemia
    100051623 (PIK3CD)
   05218 Melanoma
    100051623 (PIK3CD)
   05211 Renal cell carcinoma
    100051623 (PIK3CD)
   05215 Prostate cancer
    100051623 (PIK3CD)
   05213 Endometrial cancer
    100051623 (PIK3CD)
   05222 Small cell lung cancer
    100051623 (PIK3CD)
   05223 Non-small cell lung cancer
    100051623 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100051623 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100051623 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100051623 (PIK3CD)
   05166 HTLV-I infection
    100051623 (PIK3CD)
   05162 Measles
    100051623 (PIK3CD)
   05164 Influenza A
    100051623 (PIK3CD)
   05161 Hepatitis B
    100051623 (PIK3CD)
   05160 Hepatitis C
    100051623 (PIK3CD)
   05169 Epstein-Barr virus infection
    100051623 (PIK3CD)
   05146 Amoebiasis
    100051623 (PIK3CD)
   05145 Toxoplasmosis
    100051623 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    100051623 (PIK3CD)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100051623 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
2
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQSVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLV
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPLAGNWGA
STLRFPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRLEYLYGSYPLCRFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPTPQVQKPR
TKPPPIPVKKPSSVSLWSLEQPFCVELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGECCLYMWPSVPDEKGELLNPTGTVRNNPNTESAAALVISLPEVAP
HPVYYPALDKILELGRPGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKATKPHTKELMHLCMR
QETYLEALSHLQSPLDPSILLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccctggggttgactgccccatggaattctggaccaaggaggagaatcagagcgtg
gctgttgacttcctgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcaccatcaagaaggtgttgtggcaccgagcccagtatgagccactcttccac
atgctcagtgaccccgaggcctatgtgttcacctgcgtcaaccagactgcggagcagcag
gagctggaggacgagcagcggcggctgtgtgacatccagcccttcctgccggttctgcgc
ctggtggcccgcgagggcgacagggtgaagaagctcatcaactcgcagatcagccttgtc
atcggcaaaggcctccatgagtttgactccttgcgtgacccagaagtgaatgactttcgc
accaagatgcgccagttctgtgaggaggccgctgcccgccggcaacagctgggctgggag
gcctggctacagtacagctttcccctgcagctggagcccttggcgggaaactggggagcc
agcaccctacggttccccagccgggcccttctggtcaacgtcaagttcgagggcagtgag
gagagcttcaccttccaggtgtccaccaaggacgtgcccctggcactgatggcctgtgcc
ctccggaagaaggccacggtgttccggcagcccctggtggagcagcccgaggactacacg
ctgcaggtgaacgggagactcgagtacctgtacggcagctaccccctctgccgcttccag
tacatctgcagctgcctgcacagcgggctgacccctcatctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgaacagagcaaccccaccccccaagtccaaaaaccgcgc
accaaaccgccccccattcccgtgaagaagccctcctctgtgtccctgtggtccctggag
cagccgttctgcgtcgagctcatccagggcagcaaagtgaacgcagatgagcggatgaag
ctggtggtgcaggctgggcttttccatggtaatgagacgctctgcaagacggtgtccagc
tcggaggtgagcgtgtgctcagagcctgtgtggaaacagcggctggagtttgacatcaac
gtctgcgatctgccgcgcatggcccgtctctgctttgcactttacgccgtgattgagaag
gccaagaaggctcgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagactggggaatgctgcctctac
atgtggccctccgtcccagatgagaaaggggagctgctgaaccccacgggaaccgtgcgc
aataaccccaacactgagagcgctgccgccctggtcatctccctccccgaggtggccccc
caccccgtgtactaccctgcccttgacaagatcttggagctggggcggcccggggagcat
gggcgcttcaccgaggaggagcagctgcagctgcgggagatcctggagcggcgggggtcc
ggggagctgtatgagcatgagaaggacctggtgtggaagatgcgacacgaggtccaggag
cacttccccgaggcactggcccggctgctgctggtcaccaagtggaacaagcatgaggac
gtggcccagatgctctacctgctgtgctcctggcctgagctgcctgtgctgagcgccctg
gagctgctggacttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctg
cggaaactgacggacgacgagcttttccagtacctgctgcagctggtgcaggtgcttaag
tacgagtcctacctcgactgtgagctgaccaaattcctgctggaccgggccctggccaac
cgcaagatcggccacttcctcttctggcacctccggtccgagatgcacgtgccgtcggtg
gccctgcgcttcggcctcatcatggaggcgtactgcaggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctgaacgactttgtcaaa
gtgagctcccagaaggccaccaagccccacaccaaggagctgatgcacctgtgcatgcgc
caggagacctacctggaggccctctcccacctgcagtcgccgctcgaccccagcatcctg
ctggctgaagtctgtgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
gtcatgtacagcaacgaggaggcgggcagcgatggcagcgtgggcatcatatttaagaac
ggggatgacctccgccaggacatgctgactctgcagatgatccagctcatggacgttctg
tggaagcaggaggggttggacctgaggatgaccccctatggctgcctctccaccggggac
cgcacgggcctcatcgaggtggtgcttcactcagacaccattgccaacatccagctgaac
aagagcaacatggcagccacggccgccttcaacaaggatgccctgctcaactggctcaag
tctaagaaccctggggaggccctggaacgagctattgaggagttcaccctctcctgcgct
ggctactgtgtggccacatacgtgctgggcatcggtgatcggcacagcgacaacatcatg
atccgcgagaatgggcagctgttccacattgattttggccactttctggggaatttcaag
accaagtttggaatcaaccgtgagcgagtcccattcatcctcacctatgactttgtccat
gtgatccagcaggggaagactaataatagtgagaaattcgaaaggttccggggctactgt
gagagggcctacaccatcctgcggcgccacgggctgctcttcctgcacctcttcgccctg
atgcgggcggccggcctgcctgagctcagctgctctaaagacatccaatatctcaaggac
tctctggccttgggaaaaacggaggaggaggctctgaagcacttccgagtgaagtttaac
gaagcgctccgggagagctggaagaccaaagtgaattggctggcccacaacgtgtccaaa
gacaacaggcaatag

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