KEGG   Equus caballus (horse): 100051836Help
Entry
100051836         CDS       T01058                                 

Gene name
GCK
Definition
glucokinase (hexokinase 4)
Orthology
K12407  
glucokinase [EC:2.7.1.2]
Organism
ecb  Equus caballus (horse)
Pathway
Glycolysis / Gluconeogenesis
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Butirosin and neomycin biosynthesis
Metabolic pathways
Carbon metabolism
Insulin signaling pathway
Insulin secretion
Prolactin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100051836 (GCK)
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100051836 (GCK)
   00052 Galactose metabolism
    100051836 (GCK)
   00500 Starch and sucrose metabolism
    100051836 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100051836 (GCK)
  Biosynthesis of other secondary metabolites
   00524 Butirosin and neomycin biosynthesis
    100051836 (GCK)
 Organismal Systems
  Endocrine system
   04911 Insulin secretion
    100051836 (GCK)
   04910 Insulin signaling pathway
    100051836 (GCK)
   04917 Prolactin signaling pathway
    100051836 (GCK)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100051836 (GCK)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100051836 (GCK)
   04950 Maturity onset diabetes of the young
    100051836 (GCK)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100051836 (GCK)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
4
AA seq 466 aa AA seqDB search
MAMDARRTQAQTTLNLAEQILAEFQLQEEDLKKVMRRMQEEMDRGLRLETHEEATVKMLP
TYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTA
EMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGN
NIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGTGCNACYMEEMQ
NVELVEGDEGRMCVNTEWGAFGDAGELDEFLLEYDRVVDENSLNPGQQLCEELIGDKYMG
ELVRLVLLKLVDENLLFHGEPPMQLSTRGAFETRLVSQVESDSGDRKQIYNILSTLGLRP
SGTDCDIVRRACESVSTRAAHMCSAGLAAVINRMRESRREDVMRITVGVDGSVYKLHPSF
KQRFHASVRRLTPNCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1401 nt NT seq  +upstreamnt  +downstreamnt
atggcgatggatgccaggaggacccaggcccagacaaccttgaatctggcggagcagatc
ctggcagagttccagctgcaggaggaggacttgaagaaggtgatgaggcggatgcaggag
gagatggaccgaggcctgaggctagagacccacgaggaagccactgtgaagatgctgccc
acctacgtgcgctccaccccggaaggctcagaagtcggggacttcctctccctggacctg
ggcggcaccaacttcagggtgatgctggtgaaggtgggggagggcgaggcggggcagtgg
agtgtgaaaactaagcaccagatgtactccatccccgaggacgccatgacgggcaccgcc
gagatgctctttgactacatctccgagtgcatctctgacttcctggacaagcatcagatg
aagcacaagaagctgcccttgggcttcaccttctcctttcctgtgaggcatgaagacata
gacaagggcatccttctcaactggaccaagggcttcaaggcctctggagcagaagggaac
aacattgtggggctcctgcgagacgccatcaaacggagaggggactttgagatggacgtg
gtggcgatggtgaatgatactgtggccacaatgatctcctgctactacgaagaccgccgg
tgtgaggttggcatgattgtgggcaccggctgcaacgcctgctacatggaggagatgcag
aacgtggagctggtggaaggggacgagggccgcatgtgcgtcaacaccgagtggggcgcc
ttcggggacgcgggcgagctggacgagttcctgctggagtacgaccgcgtggtggacgag
aactccctgaaccctggccagcagctatgtgaagagctcatcggcgacaagtacatgggg
gagctggtgcggctcgtgctgctcaagcttgtggacgagaacctgctcttccacggggag
cctccgatgcagctcagcacccgcggcgccttcgagacgcgcttggtgtcgcaagtcgag
agcgactcgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgaggccc
tcgggcacggactgcgacatcgtgcgccgcgcctgcgagagcgtgtccacgcgcgccgcg
cacatgtgctccgcggggctggcggccgtcatcaaccgcatgcgcgagagccgcagggag
gacgtgatgcgcatcaccgtgggtgtagacggctcggtgtacaagctgcacccaagcttc
aagcagcggttccacgccagcgtgcgcaggctgacgcccaactgcgagatcaccttcatc
gagtcggaggagggcagcggccggggcgcggccctgatctccgcggtggcctgtaagaag
gcctgcatgctgggccagtga

DBGET integrated database retrieval system