| Entry |
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| Gene name |
ITGB8
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| Definition |
(RefSeq) integrin subunit beta 8
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| KO |
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| Organism |
ecb Equus caballus (horse)
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| Pathway |
| PI3K-Akt signaling pathway | | Focal adhesion | | ECM-receptor interaction | | Cell adhesion molecules (CAMs) | | Regulation of actin cytoskeleton | | Hypertrophic cardiomyopathy (HCM) | | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | | Dilated cardiomyopathy |
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| Brite |
KEGG Orthology (KO) [BR:ecb00001]
Environmental Information Processing
Signal transduction
04151 PI3K-Akt signaling pathway
100053462 (ITGB8)
Signaling molecules and interaction
04512 ECM-receptor interaction
100053462 (ITGB8)
04514 Cell adhesion molecules (CAMs)
100053462 (ITGB8)
Cellular Processes
Cellular community - eukaryotes
04510 Focal adhesion
100053462 (ITGB8)
Cell motility
04810 Regulation of actin cytoskeleton
100053462 (ITGB8)
Human Diseases
Cardiovascular diseases
05410 Hypertrophic cardiomyopathy (HCM)
100053462 (ITGB8)
05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
100053462 (ITGB8)
05414 Dilated cardiomyopathy (DCM)
100053462 (ITGB8)
Infectious diseases
05165 Human papillomavirus infection
100053462 (ITGB8)
Exosome [BR:ecb04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100053462 (ITGB8)
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| SSDB |
   |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: Ensembl: UniProt: |
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| Position |
4
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| AA seq |
767 aa  
MCRSTLAFFTAAFVCLQNCRPGPAPFLRAAWVFSVVLGLGQSEDNRCASSNAASCTKCLA
LGPECGWCAQEDFISGGSRSVRCDIVSNLISKGCLIDSIEYPSVHVMPSENEINTQVTPG
EVSIQLRPGAKANFMLKIHPLKQYPVDLYYLVDVSASMHNNIEKLNSVGNDLSRKMAFFS
RDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAV
HRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVV
PNDGNCHLKNNVYVRSTSMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGT
IAGEIESKAANLNNLVVEAYQKLISEVKVQVENQAKGIYFNITAICPDGTRKPGTDGCGN
VTSNDEVLFNVTVTMKKCDVTEGKSYAIIKPIGFNETTKIHIHRNCSCQCDDSRGSKRKC
VDETFLDAKCFQCDENKCHFDEDQFPSESCKSHKDQPVCSGRGVCICGKCLCHKIKLGKV
YGKYCEKDDFSCPYHQGNLCAGHGECEAGRCQCFSGWEGDRCQCPSASAQHCVNPKGQVC
SGRGTCVCGKCECTDPKSIGRFCEHCPTCHTACNENWNCVQCLHPHNLSQAILDRCKTSC
ALMEQHYVDQTSECFSSPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSADY
RVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAHETFRCNF |
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| NT seq |
2304 nt  +upstreamnt +downstreamnt
atgtgccgctcgaccctggctttttttactgccgcatttgtctgcctgcaaaactgccgg
ccaggtcctgccccattccttcgggcggcctgggtgttttcagttgttcttggactgggc
caaagtgaagacaatagatgtgcatcttcaaatgcagcgtcctgcaccaagtgccttgcg
ctgggtccggaatgtggatggtgtgcacaagaggatttcatttcaggtggatcaaggagt
gtacgttgtgatattgtttccaatttaataagcaaaggctgcttgattgattcgatagaa
tacccatctgtacatgtaatgccaagtgaaaatgaaattaatacccaggtaacaccagga
gaagtgtcgatccagctgcgtccaggagctaaagctaattttatgctgaaaattcatcct
ctgaagcaatatcctgtggatctttattatctagttgacgtctcagcatcaatgcacaat
aatattgaaaaattaaattccgttggaaatgatttatctagaaaaatggcatttttctcc
cgtgacttccgccttggatttggctcatatgttgataaaacagtttcaccatacattagc
atccacccagaaaggattcataatcaatgcagtgactacaatttagactgtatgcctccc
catggatacatccatgtgctgtctttgacggagaacatcactgagtttgaaaaagcagta
cacagacagaagatctctggaaatatagatacgcctgaaggaggttttgatgccatgctt
caggcagctgtctgtgagagtcatattggatggcgaaaagaagctaaaagattgctgctg
gtgatgacagatcagacatctcatcttgctcttgatagcaaattggcaggcatcgtggtg
ccaaatgacggaaactgccatctgaaaaacaacgtctatgtcagatcaacaagcatggaa
catccctcactaggccaactttcagaaaagttaatagacaacaacattaacgtcatattt
gcagttcaaggaaaacagtttcattggtataaggaccttctacccctcttgcctggcaca
attgctggtgaaatagaatcaaaggctgcaaacctcaataatttggtagtagaagcctat
cagaaactcatttcagaagtgaaagttcaggtggaaaaccaggcaaaaggcatctatttt
aacattactgccatctgcccagatgggaccagaaagccaggcacagacggatgtggaaat
gtgacaagcaatgacgaggttcttttcaatgtaacagttacaatgaaaaaatgtgatgtc
acagaaggaaaaagctatgcaataatcaaacctattggtttcaatgaaaccactaaaatt
catatacacagaaactgcagctgtcagtgtgatgacagcagaggatctaaaaggaagtgt
gtagatgaaacttttctagatgccaagtgtttccagtgtgatgagaataaatgtcacttt
gatgaagatcaatttccttctgagagttgcaagtcacacaaggatcaacctgtttgcagc
ggtcgaggagtctgtatttgtgggaaatgtttatgtcacaaaattaagcttggaaaagtg
tatggaaaatactgtgaaaaggatgacttttcttgtccataccaccagggaaatctgtgt
gcggggcacggagagtgtgaagcgggcagatgccagtgcttcagtggctgggaaggggat
cggtgccagtgcccatcagcatcagcccagcactgtgtcaacccaaagggccaagtatgt
agtggaagaggcacatgtgtatgtggcaagtgtgagtgcaccgatcccaagagcatcggc
cgcttctgtgaacactgccccacatgtcacacagcctgcaatgaaaactggaattgtgtg
caatgccttcaccctcacaatctgtctcaagctatacttgatcggtgtaaaacctcatgt
gctctcatggaacagcattatgtagaccaaacatcagaatgtttctctagcccaagctac
ttgagaatatttttcatcatcttcatagttacattcttgattgggttgcttaaagtcctt
atcattagacaggtgatactacaatggaatagtaataaaattaagtcctcagcagattac
agagtgtcagcctcaaaaaaggacaagttgattctgcaaagtgtttgcacaagagcagta
acttaccgacgtgagaaacctgaagaaataaaaatggatatcagcaaattaaatgctcat
gaaacgttcaggtgcaacttttaa |
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