KEGG   Equus caballus (horse): 100053889Help
Entry
100053889         CDS       T01058                                 

Gene name
SOS1
Definition
son of sevenless homolog 1 (Drosophila)
Orthology
K03099  
son of sevenless
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
PI3K-Akt signaling pathway
Dorso-ventral axis formation
Focal adhesion
Gap junction
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Prolactin signaling pathway
Alcoholism
Hepatitis C
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Renal cell carcinoma
Endometrial cancer
Glioma
Prostate cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100053889 (SOS1)
   04010 MAPK signaling pathway
    100053889 (SOS1)
   04012 ErbB signaling pathway
    100053889 (SOS1)
   04630 Jak-STAT signaling pathway
    100053889 (SOS1)
   04068 FoxO signaling pathway
    100053889 (SOS1)
   04151 PI3K-Akt signaling pathway
    100053889 (SOS1)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100053889 (SOS1)
  Cellular commiunity
   04510 Focal adhesion
    100053889 (SOS1)
   04540 Gap junction
    100053889 (SOS1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100053889 (SOS1)
   04660 T cell receptor signaling pathway
    100053889 (SOS1)
   04662 B cell receptor signaling pathway
    100053889 (SOS1)
   04664 Fc epsilon RI signaling pathway
    100053889 (SOS1)
   04062 Chemokine signaling pathway
    100053889 (SOS1)
  Endocrine system
   04910 Insulin signaling pathway
    100053889 (SOS1)
   04912 GnRH signaling pathway
    100053889 (SOS1)
   04915 Estrogen signaling pathway
    100053889 (SOS1)
   04917 Prolactin signaling pathway
    100053889 (SOS1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100053889 (SOS1)
  Development
   04320 Dorso-ventral axis formation
    100053889 (SOS1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100053889 (SOS1)
   05206 MicroRNAs in cancer
    100053889 (SOS1)
   05205 Proteoglycans in cancer
    100053889 (SOS1)
   05214 Glioma
    100053889 (SOS1)
   05221 Acute myeloid leukemia
    100053889 (SOS1)
   05220 Chronic myeloid leukemia
    100053889 (SOS1)
   05211 Renal cell carcinoma
    100053889 (SOS1)
   05215 Prostate cancer
    100053889 (SOS1)
   05213 Endometrial cancer
    100053889 (SOS1)
   05223 Non-small cell lung cancer
    100053889 (SOS1)
  Substance dependence
   05034 Alcoholism
    100053889 (SOS1)
  Infectious diseases
   05160 Hepatitis C
    100053889 (SOS1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
15
AA seq 1333 aa AA seqDB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVNRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKDLINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISE
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq 4002 nt NT seq  +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaggaattaattttgcagttattaaatatgctatgc
caagctcagcctcgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccgattgataagtgggcaatagctgatgcccagtcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagagtatatttctgcagac
attttaaagctggtagggaattatgtacggaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacacgaacttagtgtaaagttactg
ggccacatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggctttcatgatcatttccttagtcagctatcaaagcctggagca
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggatgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcgaatcatgggcaaccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaggagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagccc
gactctgaagagaatattatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccacatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaactg
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaaggtttagaaaagag
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagaacaccac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaacttactttacttgaatcagatctgtatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcacaccactaatctcactttgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgaatcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggcgtccttgaggttgttagtgctatgaactca
tcacctgtttacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctgaaaaggcatggaaaagaccttataaactttagcaaa
aggaggaaggtagcagaaattacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcggatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggagaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaat
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagagagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttccagtaccacagat
gtttgcagcgtatttgattctgatcattcgagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaaaggcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgctattcaatatcagag
cggacctctatatcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttctccctttacaccacctcct
cctcaaacaccttctcctcacggcacgagaaggcatctgccgtcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcccgttcctcctcgacaaagcacttctcag
catatccctaaactccctcccaaaacttacaaaagggagcacacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga

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